SCHEMBL4277997

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8374009	0.92	CXCR3 (0.48)	CXCR3EPHX2LMNAALDH1A1NAMPT
	SCHEMBL4278127	0.89	CXCR3 (0.56)	CXCR3EPHX2LMNAALDH1A1NAMPT
	SCHEMBL12004810	0.89	CXCR3 (0.53)	CXCR3EPHX2LMNAALDH1A1NAMPT
	SCHEMBL4271452	0.87	CXCR3 (0.54)	CXCR3EPHX2LMNAALDH1A1NAMPT
	SCHEMBL6862660	0.86	CXCR3 (0.48)	CXCR3EPHX2LMNAALDH1A1NAMPT
	SCHEMBL1445327	0.84	LMNA (0.52)	CXCR3EPHX2LMNAALDH1A1NAMPT
	SCHEMBL12005795	0.83	CXCR3 (0.50)	CXCR3EPHX2LMNAALDH1A1NAMPT
	SCHEMBL6863335	0.83	STS (0.56)	CXCR3EPHX2MAPTTACR1
	SCHEMBL4273193	0.83	CXCR3 (0.46)	CXCR3EPHX2LMNAALDH1A1NAMPT
	SCHEMBL6863165	0.82	CXCR3 (0.47)	CXCR3EPHX2LMNAALDH1A1NAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.