Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | JUN | P05412 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | GUSB | P08236 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13176953 | 0.85 | NFKB1 (0.47) | IAPPMAPTLMNANFKB1CA1 | |
| SCHEMBL10962113 | 0.82 | MAPT (0.66) | IAPPMAPTLMNANFKB1CA1 | |
| SCHEMBL18231255 | 0.81 | IAPP (0.44) | IAPPMAPTLMNANFKB1CA1 | |
| SCHEMBL24425997 | 0.80 | CYP3A4 (0.45) | IAPPMAPTLMNAKDM4E | |
| SCHEMBL10589353 | 0.79 | NFKB1 (0.69) | IAPPMAPTLMNANFKB1CA1 | |
| SCHEMBL19732049 | 0.79 | KDM4E (0.51) | MAPTLMNAATMNFE2L2ERN1 | |
| SCHEMBL15481177 | 0.79 | IAPP (0.49) | IAPPMAPTLMNANFKB1CA1 | |
| SCHEMBL8661727 | 0.78 | MAPT (0.47) | IAPPMAPTLMNANFKB1CA1 | |
| SCHEMBL10045014 | 0.77 | IAPP (0.47) | IAPPMAPTLMNANFKB1CA1 | |
| SCHEMBL27773602 | 0.76 | TRPA1 (0.48) | IAPPMAPTLMNANFKB1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7261954-B2 | Organic light emitting devices having carrier blocking layers comprising metal complexes | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2007-08-28 | — | — | US | disclosed |