SCHEMBL19732049

SCHEMBL19732049

C=C(C)/C=C\c1cccc(OC)c1C

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 3/20 0.51
▸ NFE2L2 Q16236 4/20 0.49
▸ TFEB P19484 1/20 0.49
▸ MEN1 O00255 2/20 0.46
▸ KMT2A Q03164 2/20 0.46
▸ ALDH1A1 P00352 1/20 0.46
▸ CYP3A4 P08684 1/20 0.46
▸ TLR2 O60603 1/20 0.46
▸ ERN1 O75460 1/20 0.46
▸ TLR1 Q15399 1/20 0.46
▸ TLR6 Q9Y2C9 1/20 0.46
▸ MAPT P10636 3/20 0.44
▸ NPC1 O15118 2/20 0.44
▸ RAB9A P51151 2/20 0.44
▸ LMNA P02545 2/20 0.44
▸ BCHE P06276 1/20 0.44
▸ MAPK1 P28482 1/20 0.43
▸ ATM Q13315 1/20 0.43
▸ NPSR1 Q6W5P4 1/20 0.43
▸ TDP1 Q9NUW8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15481174 0.83 KDM4E (0.51) KDM4ENFE2L2TFEBMEN1KMT2A
SCHEMBL31689790 0.81 NFE2L2 (0.55) KDM4ENFE2L2TFEBTLR2ERN1
SCHEMBL31689795 0.81 NFE2L2 (0.55) KDM4ENFE2L2TFEBTLR2ERN1
SCHEMBL9689786 0.79 KDM4E (0.68) KDM4ENFE2L2TFEBALDH1A1MAPT
SCHEMBL16831490 0.79 KDM4E (0.68) KDM4ENFE2L2TFEBALDH1A1MAPT
SCHEMBL14448435 0.79 IAPP (0.47) KDM4ENFE2L2MEN1KMT2AERN1
SCHEMBL24425997 0.77 CYP3A4 (0.45) KDM4EALDH1A1CYP3A4MAPTLMNA
SCHEMBL17813094 0.75 KDM4E (0.44) KDM4ENFE2L2TFEBMEN1KMT2A
SCHEMBL25555199 0.75 NFE2L2 (0.46) KDM4ENFE2L2TFEBMEN1KMT2A
SCHEMBL8661727 0.75 MAPT (0.47) KDM4ENFE2L2TFEBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230320193-A1 HETEROCYCLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING HETEROCYCLIC COMPOUND, AND ELECTRONIC APPARATUS INCLUDING LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-10-05 — — US disclosed
US-20230225204-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-13 — — US disclosed
US-20230159570-A1 LIGHT-EMITTING DEVICE INCLUDING HETEROCYCLIC COMPOUND, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND THE HETEROCYCLIC COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-25 — — US disclosed
US-20210359214-A1 ORGANIC LIGHT-EMITTING DEVICE AND APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2021-11-18 — — US disclosed
US-10553797-B2 Fluorene derivative, light-emitting elements, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2020-02-04 — — US disclosed
US-20170365782-A1 FLUORENE DERIVATIVE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-12-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170365782-A1 FLUORENE DERIVATIVE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE NR2E3, NR2E1, AFF1 KDM4E 2103/4885NFE2L2 55/4885TFEB 424/4885
US-20230320193-A1 HETEROCYCLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING HETEROCYCLIC COMPOUND, AND ELECTRONIC APPARATUS INCLUDING LIGHT-EMITTING DEVICE CYP1A1, CRY1, CYP1B1 KDM4E 3342/4885NFE2L2 76/4885TFEB 178/4885
US-20230159570-A1 LIGHT-EMITTING DEVICE INCLUDING HETEROCYCLIC COMPOUND, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND THE HETEROCYCLIC COMPOUND CRY1, CYP1A1, NQO1 KDM4E 3633/4885NFE2L2 66/4885TFEB 145/4885
US-10553797-B2 Fluorene derivative, light-emitting elements, light-emitting device, electronic device, and lighting device NR2E3, GRK1, AFF1 KDM4E 2236/4885NFE2L2 82/4885TFEB 546/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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