Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10075193 | 0.81 | MEN1 (0.43) | KMT2AMAPTALDH1A1MEN1LMNA | |
| SCHEMBL13273168 | 0.81 | MEN1 (0.43) | KMT2AMAPTALDH1A1MEN1LMNA | |
| SCHEMBL14307041 | 0.80 | NR1I2 (0.48) | MAPTALDH1A1HPGDLMNAMAPK1 | |
| SCHEMBL4526167 | 0.77 | RXFP1 (0.47) | KMT2AMAPTALDH1A1HPGDMEN1 | |
| SCHEMBL1350080 | 0.75 | DGAT1 (0.53) | KMT2AMAPTALDH1A1HPGDMEN1 | |
| Hydrochloric Acid SCHEMBL156995 | 0.73 | DGAT1 (0.51) | KMT2AMAPTALDH1A1HPGDMEN1 | |
| SCHEMBL28911954 | 0.73 | RXFP1 (0.43) | KMT2AMAPTALDH1A1HPGDMEN1 | |
| SCHEMBL11444418 | 0.71 | ALDH1A1 (0.47) | KMT2AMAPTALDH1A1HPGDMEN1 | |
| SCHEMBL274513 | 0.71 | CA1 (0.68) | KMT2AMAPTALDH1A1HPGDMEN1 | |
| SCHEMBL13921790 | 0.71 | NPC1 (0.47) | LMNAMAPK1RXFP1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7262223-B2 | Amidine derivatives for treating amyloidosis | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2007-08-28 | — | — | US | disclosed |