SCHEMBL4526167

SCHEMBL4526167

CCO/C(=N\C(=O)c1ccc(Br)cc1)c1ccc(Br)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 2/20 0.47
MAPT P10636 4/20 0.44
KMT2A Q03164 4/20 0.44
ALDH1A1 P00352 2/20 0.44
HPGD P15428 2/20 0.44
LMNA P02545 3/20 0.44
MEN1 O00255 2/20 0.44
MAPK1 P28482 2/20 0.44
NPSR1 Q6W5P4 2/20 0.44
S1PR4 O95977 1/20 0.44
S1PR1 P21453 1/20 0.44
NHERF1 O14745 1/20 0.43
HTT P42858 2/20 0.42
RAB9A P51151 2/20 0.40
NPC1 O15118 1/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
ESR1 P03372 1/20 0.40
CA7 P43166 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28911954 0.94 RXFP1 (0.43) RXFP1MAPTKMT2AALDH1A1HPGD
SCHEMBL13921790 0.88 NPC1 (0.47) RXFP1LMNAMAPK1RAB9ANPC1
SCHEMBL5201790 0.83 RXFP1 (0.47) RXFP1MAPTKMT2AALDH1A1HPGD
SCHEMBL5205877 0.83 RXFP1 (0.47) RXFP1MAPTKMT2AALDH1A1HPGD
SCHEMBL22208242 0.83 MEN1 (0.47) MAPTKMT2AALDH1A1LMNAMEN1
SCHEMBL22208244 0.83 MEN1 (0.47) MAPTKMT2AALDH1A1LMNAMEN1
SCHEMBL17348463 0.80 CYP19A1 (0.46) RXFP1MAPTKMT2AALDH1A1HPGD
SCHEMBL4520536 0.80 SMN1; SMN2 (0.50) MAPTKMT2AALDH1A1HPGDLMNA
SCHEMBL4520539 0.80 SMN1; SMN2 (0.50) MAPTKMT2AALDH1A1HPGDLMNA
SCHEMBL14448784 0.77 KMT2A (0.41) RXFP1MAPTKMT2AALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10333078-B2 Fluorescent organic light emitting elements having high efficiency UDC IRELAND LIMITED (IE) 2019-06-25 US disclosed
US-20170309828-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency BASF SE (DE) 2017-10-26 US disclosed
US-20170309828-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency BASF SE (DE) 2017-10-26 US disclosed
WO-2016046350-A1 FLUORESCENT ORGANIC LIGHT EMITTING ELEMENTS HAVING HIGH EFFICIENCY BASF SE (DE) 2016-03-31 WO disclosed
US-9113536-B2 Electroluminescent device BASF SE (DE) 2015-08-18 US disclosed
US-9113536-B2 Electroluminescent device BASF SE (DE) 2015-08-18 US disclosed
US-9113536-B2 Electroluminescent device BASF SE (DE) 2015-08-18 US disclosed
US-20090066231-A1 Electroluminescent device UDC IRELAND LIMITED (IE) 2009-03-12 US disclosed
US-20090066231-A1 Electroluminescent device UDC IRELAND LIMITED (IE) 2009-03-12 US disclosed
US-20090066231-A1 Electroluminescent device UDC IRELAND LIMITED (IE) 2009-03-12 US disclosed
EP-1874740-A1 ELECTROLUMINESCENT DEVICE CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) 2008-01-09 EP disclosed
WO-2006114377-A1 ELECTROLUMINESCENT DEVICE CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-11-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10333078-B2 Fluorescent organic light emitting elements having high efficiency NR2E3, CRY1, ALDH1A2 RXFP1 2147/4885MAPT 2708/4885KMT2A 1982/4885
US-20090066231-A1 Electroluminescent device CD99, TEC, TYR RXFP1 3924/4885MAPT 561/4885KMT2A 2657/4885
US-20170309828-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency NR2E3, CRY1, ALDH1A2 RXFP1 2147/4885MAPT 2708/4885KMT2A 1982/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.