Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | XDH | P47989 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.64 |
| ▸ | GFER | P55789 | 1/20 | 0.64 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.64 |
| ▸ | RELA | Q04206 | 1/20 | 0.64 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | CNR2 | P34972 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 3/20 | 0.55 |
| ▸ | CA1 | P00915 | 3/20 | 0.55 |
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | CA7 | P43166 | 3/20 | 0.55 |
| ▸ | CA9 | Q16790 | 3/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1919075 | 0.90 | KDM4E (0.72) | LMNAKDM4EXDHTDP1POLB | |
| SCHEMBL2605591 | 0.89 | CA1 (0.60) | LMNAKDM4EXDHTDP1POLB | |
| SCHEMBL3353446 | 0.84 | LMNA (0.77) | LMNAKDM4EXDHTDP1POLB | |
| SCHEMBL27898473 | 0.82 | LMNA (0.62) | LMNAKDM4EXDHTDP1POLB | |
| SCHEMBL198717 | 0.81 | KDM4E (0.65) | LMNAKDM4EXDHTDP1POLB | |
| SCHEMBL22114782 | 0.81 | GAA (0.60) | LMNAKDM4EXDHTDP1POLB | |
| SCHEMBL26579409 | 0.81 | LMNA (0.60) | LMNAKDM4EXDHTDP1POLB | |
| SCHEMBL9944141 | 0.81 | LMNA (0.60) | LMNAKDM4EXDHTDP1POLB | |
| SCHEMBL6066809 | 0.81 | CNR2 (0.62) | LMNAKDM4EXDHTDP1POLB | |
| SCHEMBL29555188 | 0.81 | KDM4E (0.66) | LMNAKDM4EXDHTDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016126941-A1 | MULTIMERIC PROTECTED FLUORESCENT REAGENTS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2016-08-11 | — | — | WO | disclosed |
| US-7244730-B2 | 2-iminopyrrolidine derivatives | EISAI CO., LTD (JP) | 2007-07-17 | — | — | US | disclosed |