Sugi Predict

Sugi Predict / Compounds / SCHEMBL198717

SCHEMBL198717

SCHEMBL198717

COC(=O)c1cc(C)c(O)c(C)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 5/20 0.65
▸ TDP1 Q9NUW8 3/20 0.65
▸ LMNA P02545 3/20 0.65
▸ XDH P47989 2/20 0.65
▸ POLB P06746 1/20 0.65
▸ GAA P10253 1/20 0.65
▸ NFKB1 P19838 1/20 0.65
▸ GFER P55789 1/20 0.65
▸ NFKB2 Q00653 1/20 0.65
▸ RELA Q04206 1/20 0.65
▸ FUT7 Q11130 1/20 0.65
▸ L3MBTL1 Q9Y468 1/20 0.65
▸ CA12 O43570 3/20 0.61
▸ CA1 P00915 3/20 0.61
▸ CA2 P00918 3/20 0.61
▸ CA7 P43166 3/20 0.61
▸ CA9 Q16790 3/20 0.61
▸ CA14 Q9ULX7 3/20 0.61
▸ ESR1 P03372 2/20 0.55
▸ CNR2 P34972 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3353446 0.90 LMNA (0.77) KDM4ETDP1LMNAXDHPOLB
SCHEMBL21854475 0.88 KDM4E (0.57) KDM4ETDP1LMNAXDHPOLB
SCHEMBL399550 0.88 KDM4E (0.57) KDM4ETDP1LMNAXDHPOLB
SCHEMBL750862 0.86 KDM4E (0.55) KDM4ETDP1LMNAXDHPOLB
SCHEMBL31395255 0.86 KDM4E (0.60) KDM4ETDP1LMNAXDHPOLB
SCHEMBL402146 0.86 KDM4E (0.55) KDM4ETDP1LMNAXDHPOLB
SCHEMBL399645 0.86 KDM4E (0.60) KDM4ETDP1LMNAXDHPOLB
SCHEMBL401708 0.86 KDM4E (0.55) KDM4ETDP1LMNAXDHPOLB
SCHEMBL14466473 0.86 KDM4E (0.55) KDM4ETDP1LMNAXDHPOLB
SCHEMBL2605591 0.86 CA1 (0.60) KDM4ETDP1LMNAXDHPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 183 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113748021-B Method for producing liquid crystal polyester processed product 本州化学工业株式会社 2024-07-05 — — CN claimed
CN-110093064-B Preparation method and application of long-afterglow luminescent ink 重庆理工大学 2021-07-13 — — CN claimed
US-4937281-A ACRYLIC BINDER OF ALKYL ACRYLATES HAVING PENDANT AMINOESTERS OR HYDROXYAMINO ESTER GROUPS, SOLVENT AND AN ALKYL P-HYDROXY BENZOATE AS CURING CATALYST; AUTO REFINISHES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-06-26 — — US claimed
US-4895768-A CROSSLINKED ACRYLIC ESTER E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-01-23 — — US claimed
CN-122055358-A GPR65 small molecule regulator and preparation method and application thereof 四川大学 2026-05-15 — — CN disclosed
US-20250333424-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. 2025-10-30 — — US disclosed
US-20250313574-A1 SIALIC ACID DERIVATIVES AND METHODS OF USING SAME EISAI R&D MANAGEMENT CO., LTD. (JP) 2025-10-09 — — US disclosed
US-12421452-B2 Method for producing liquid-crystal polyester processed product HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2025-09-23 — — US disclosed
US-20250188044-A1 TRIAZOLONE COMPOUND, PHARMACEUTICAL USE THEREOF AND PHARMACEUTICAL COMPOSITION HARBIN MEDISAN PHARMACEUTICAL CO., LTD. (CN) 2025-06-12 — — US disclosed
EP-4536653-A2 SIALIC ACID DERIVATIVES AND METHODS OF USING SAME Eisai R&D Management Co., Ltd. (JP) 2025-04-16 — — EP disclosed
CN-118440180-A Fluorinated albumin and synthesis method and application thereof 中国科学院精密测量科学与技术创新研究院 2024-08-06 — — CN disclosed
CN-113748021-B Method for producing liquid crystal polyester processed product 本州化学工业株式会社 2024-07-05 — — CN disclosed
WO-2000007972-A1 GLUCOCORTICOID AND THYROID HORMONE RECEPTOR LIGANDS FOR THE TREATMENT OF METABOLIC DISORDERS KARO BIO AB (SE) 2000-02-17 — — WO disclosed
US-5643929-A TREATMENT OF PICORNAVIRAL OR RHINOVIRUS AND CHEMICAL INTERMEDIATES SANOFI WINTHROP, INC. (US) 1997-07-01 — — US disclosed
US-5464848-A 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents STERLING WINTHROP INC. (US) 1995-11-07 — — US disclosed
US-5039781-A Polyphenylene ether end capped with oxazoline moiety HUELS AKTIENGESELLSCHAFT (DE) 1991-08-13 — — US disclosed
US-4937281-A ACRYLIC BINDER OF ALKYL ACRYLATES HAVING PENDANT AMINOESTERS OR HYDROXYAMINO ESTER GROUPS, SOLVENT AND AN ALKYL P-HYDROXY BENZOATE AS CURING CATALYST; AUTO REFINISHES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-06-26 — — US disclosed
US-4895768-A CROSSLINKED ACRYLIC ESTER E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-01-23 — — US disclosed
US-4120846-A Benzoyloxybenzoates and compositions stabilized therewith CIBA-GEIGY CORPORATION (US) 1978-10-17 — — US disclosed
US-4051104-A Benzoyloxybenzoates and compositions stabilized therewith CIBA-GEIGY CORPORATION (US) 1977-09-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250188044-A1 TRIAZOLONE COMPOUND, PHARMACEUTICAL USE THEREOF AND PHARMACEUTICAL COMPOSITION PPARD, PPARA, PPARG KDM4E 4377/4885TDP1 3079/4885LMNA 2125/4885
US-20250313574-A1 SIALIC ACID DERIVATIVES AND METHODS OF USING SAME NEU1, NEU2, NEU4 KDM4E 4207/4885TDP1 2619/4885LMNA 1117/4885
US-20250333424-A1 ANTIVIRAL COMPOUNDS MAVS, EIF2AK2, IRF3 KDM4E 2765/4885TDP1 360/4885LMNA 3393/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.