Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL899936 | 1.00 | ALDH1A1 (0.46) | ALDH1A1KMT2ARAB9AHPGDPOLB | |
| SCHEMBL20224715 | 0.96 | ALDH1A1 (0.44) | ALDH1A1KMT2ARAB9AHPGDPOLB | |
| SCHEMBL14435506 | 0.91 | LMNA (0.47) | ALDH1A1KMT2ARAB9AHPGDPOLB | |
| SCHEMBL899899 | 0.91 | LMNA (0.47) | ALDH1A1KMT2ARAB9AHPGDPOLB | |
| SCHEMBL7193500 | 0.90 | ALDH1A1 (0.42) | ALDH1A1KMT2ARAB9AHPGDPOLB | |
| SCHEMBL900051 | 0.86 | ALDH1A1 (0.44) | ALDH1A1KMT2ARAB9AHPGDPOLB | |
| SCHEMBL17147581 | 0.86 | ALDH1A1 (0.44) | ALDH1A1KMT2ARAB9AHPGDPOLB | |
| SCHEMBL25568729 | 0.86 | KMT2A (0.43) | ALDH1A1KMT2ARAB9AHPGDPOLB | |
| SCHEMBL200507 | 0.85 | ALDH1A1 (0.49) | ALDH1A1KMT2ARAB9AHPGDPOLB | |
| SCHEMBL2754655 | 0.85 | ALDH1A1 (0.49) | ALDH1A1KMT2ARAB9AHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1815838-A1 | Solid materials obtainable by the ring-opening methathesis polymerization | 3M Innovative Properties Company (US) | 2007-08-08 | — | — | EP | disclosed |