SCHEMBL899899

SCHEMBL899899

O=C(OCC(COC(=O)C1CC2C=CC1C2)(COC(=O)C1CC2C=CC1C2)COC(=O)C1CC2C=CC1C2)C1CC2C=CC1C2

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.47
KDM4E B2RXH2 2/20 0.47
ALDH1A1 P00352 10/20 0.47
KMT2A Q03164 3/20 0.47
RAB9A P51151 1/20 0.47
POLB P06746 3/20 0.45
HSD17B10 Q99714 2/20 0.45
APEX1 P27695 1/20 0.45
RECQL P46063 1/20 0.45
BLM P54132 1/20 0.45
ESR2 Q92731 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
HPGD P15428 1/20 0.45
MAPK1 P28482 2/20 0.38
MAPT P10636 1/20 0.38
MEN1 O00255 1/20 0.37
ALOX15 P16050 1/20 0.37
TSHR P16473 1/20 0.37
HTT P42858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14435506 1.00 LMNA (0.47) LMNAKDM4EALDH1A1KMT2ARAB9A
SCHEMBL17147581 0.95 ALDH1A1 (0.44) LMNAKDM4EALDH1A1KMT2ARAB9A
SCHEMBL900051 0.92 ALDH1A1 (0.44) LMNAKDM4EALDH1A1KMT2ARAB9A
SCHEMBL14449129 0.91 ALDH1A1 (0.46) LMNAKDM4EALDH1A1KMT2ARAB9A
SCHEMBL899936 0.91 ALDH1A1 (0.46) LMNAKDM4EALDH1A1KMT2ARAB9A
SCHEMBL23228322 0.87 ALDH1A1 (0.46) LMNAKDM4EALDH1A1KMT2ARAB9A
SCHEMBL13819402 0.87 ALDH1A1 (0.45) LMNAKDM4EALDH1A1KMT2ARAB9A
SCHEMBL4400475 0.87 ALDH1A1 (0.46) LMNAKDM4EALDH1A1KMT2ARAB9A
SCHEMBL17616838 0.87 ALDH1A1 (0.45) LMNAKDM4EALDH1A1KMT2ARAB9A
SCHEMBL14449005 0.87 ALDH1A1 (0.46) LMNAKDM4EALDH1A1KMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747632-A2 MICROFLUIDIC ENZYME ASSAYS University of Helsinki (FI) 2026-05-27 EP claimed
WO-2025016830-A2 MICROFLUIDIC ENZYME ASSAYS UNIVERSITY OF HELSINKI (FI) 2025-01-23 WO claimed
US-12054607-B2 Tough, healable composites displaying stress relaxation at the resin-filler interface THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2024-08-06 US claimed
US-20210002469-A1 TOUGH, HEALABLE COMPOSITES DISPLAYING STRESS RELAXATION AT THE RESIN-FILLER INTERFACE NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2021-01-07 US claimed
WO-2019183140-A1 TOUGH, HEALABLE COMPOSITES DISPLAYING STRESS RELAXATION AT THE RESIN-FILLER INTERFACE THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2019-09-26 WO claimed
EP-2847245-B1 METHOD FOR THE MANUFACTURE OF COATED ARTICLES AND COATED ARTICLES MERCENE LABS AB (SE) 2019-01-02 EP claimed
US-9862857-B2 Method and formulations for the manufacture of coated articles and composites MERCENE LABS AB (SE) 2018-01-09 US claimed
US-20160369127-A1 METHOD AND FORMULATIONS FOR THE MANUFACTURE OF COATED ARTICLES AND COMPOSITES MERCENE LABS AB (SE) 2016-12-22 US claimed
US-9523019-B2 Method and formulations for the manufacture of coated articles and composites MERCENE LABS AB (SE) 2016-12-20 US claimed
EP-2622002-B1 METHOD FOR THE MANUFACTURE OF ARTICLES OF THIOL-ENE POLYMERS MERCENE LABS AB (SE) 2016-02-24 EP claimed
US-8927664-B2 Method for the manufacture of articles of thiol-ene polymers MERCENE LABS AB (SE) 2015-01-06 US claimed
US-20130331528-A1 METHOD FOR THE MANUFACTURE OF ARTICLES OF THIOL-ENE POLYMERS MERCENE LABS AB (SE) 2013-12-12 US claimed
WO-2013167576-A2 METHOD AND FORMULATIONS FOR THE MANUFACTURE OF COATED ARTICLES AND COMPOSITES MERCENE LABS AB (SE) 2013-11-14 WO claimed
EP-2622002-A1 METHOD FOR THE MANUFACTURE OF ARTICLES OF THIOL-ENE POLYMERS Mercene Labs AB (SE) 2013-08-07 EP claimed
US-20130123381-A1 Novel Resin Systems for Dental Restorative Materials and Methods Using Same THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2013-05-16 US claimed
US-20120256338-A1 NEW RESIN SYSTEMS FOR DENTAL RESTORATIVE MATERIALS THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2012-10-11 US claimed
US-8192673-B2 Resin systems for dental restorative materials UNIVERSITY OF KANSAS (US) 2012-06-05 US claimed
WO-2012042059-A1 METHOD FOR THE MANUFACTURE OF ARTICLES OF THIOL-ENE POLYMERS CARLBORG CARL FREDRIK (SE) 2012-04-05 WO claimed
WO-2010114760-A1 NEW RESIN SYSTEMS FOR DENTAL RESTORATIVE MATERIALS THE REGENTS OF THE UNIVERSITY OF COLORADO (US) 2010-10-07 WO claimed
US-20090270528-A1 RESIN SYSTEMS FOR DENTAL RESTORATIVE MATERIALS THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2009-10-29 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12054607-B2 Tough, healable composites displaying stress relaxation at the resin-filler interface CRH, CNKSR1, RAD51 LMNA 2108/4885KDM4E 570/4885ALDH1A1 3679/4885
US-20210002469-A1 TOUGH, HEALABLE COMPOSITES DISPLAYING STRESS RELAXATION AT THE RESIN-FILLER INTERFACE CRH, CNKSR1, RAD51 LMNA 2108/4885KDM4E 570/4885ALDH1A1 3679/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.