Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | LSS | P48449 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | TERT | O14746 | 1/20 | 0.38 |
| ▸ | ATP4A | P20648 | 1/20 | 0.38 |
| ▸ | ATP4B | P51164 | 1/20 | 0.38 |
| ▸ | TOP1 | P11387 | 2/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14449216 | 1.00 | THRA (0.41) | THRATHRBHTR1AHTR1DHTR1B | |
| SCHEMBL14449234 | 1.00 | THRA (0.41) | THRATHRBHTR1AHTR1DHTR1B | |
| SCHEMBL14449245 | 1.00 | THRA (0.41) | THRATHRBHTR1AHTR1DHTR1B | |
| SCHEMBL12427960 | 0.94 | LSS (0.44) | LSSKDM4EALDH1A1SMN1; SMN2ALOX5 | |
| SCHEMBL14449207 | 0.93 | THRA (0.46) | THRATHRBHTR1AHTR1DHTR1B | |
| SCHEMBL12057441 | 0.93 | TERT (0.43) | KDM4EALDH1A1SMN1; SMN2TERTTOP1 | |
| SCHEMBL12057400 | 0.93 | TERT (0.43) | KDM4EALDH1A1SMN1; SMN2TERTTOP1 | |
| SCHEMBL12057450 | 0.93 | TERT (0.43) | KDM4EALDH1A1SMN1; SMN2TERTTOP1 | |
| SCHEMBL12428034 | 0.93 | TERT (0.43) | KDM4EALDH1A1SMN1; SMN2TERTTOP1 | |
| SCHEMBL12057440 | 0.93 | TERT (0.43) | KDM4EALDH1A1SMN1; SMN2TERTTOP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070167619-A1 | Novel uses of porphyrin compounds | DESTINY PHARMA LTD. (GB) | 2007-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070167619-A1 | Novel uses of porphyrin compounds | PPOX, ZFX, ZYX | THRA 3801/4885THRB 3949/4885HTR1A 3348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.