Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20349567 | 0.85 | HSD11B1 (0.47) | EPHX1EPHX2DRD2HSD11B1SLC6A5 | |
| SCHEMBL25568030 | 0.84 | HSD11B1 (0.47) | DRD2HSD11B1 | |
| SCHEMBL12282454 | 0.80 | HSD11B1 (0.50) | DRD2HSD11B1KDM4EALDH1A1 | |
| SCHEMBL20970613 | 0.78 | EPHX1 (0.59) | EPHX1EPHX2CCR1MEN1KMT2A | |
| SCHEMBL11960652 | 0.77 | EPHX1 (0.57) | EPHX1EPHX2SLC6A5CCR1HTR4 | |
| SCHEMBL103089 | 0.76 | HSD11B1 (0.47) | EPHX1EPHX2DRD2HSD11B1L3MBTL1 | |
| SCHEMBL20061838 | 0.75 | CCR1 (0.51) | EPHX1EPHX2CCR1HTR4CHRM3 | |
| SCHEMBL12283608 | 0.75 | L3MBTL1 (0.56) | HSD11B1L3MBTL1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14252361 | 0.75 | HSD11B1 (0.49) | EPHX1EPHX2DRD2HSD11B1ALDH1A1 | |
| SCHEMBL18676271 | 0.75 | EPHX1 (0.54) | EPHX1EPHX2L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241763-B2 | 3-furanyl analogs of toxoflavine as kinase inhibitors | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-07-10 | — | — | US | disclosed |