Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | UBE2M | P61081 | 1/20 | 0.47 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | CCR5 | P51681 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17285628 | 0.87 | EPHX1 (0.51) | EPHX1EPHX2L3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL27872386 | 0.85 | CCR5 (0.43) | EPHX1EPHX2L3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL12971748 | 0.84 | KCNA3 (0.57) | EPHX1EPHX2L3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL13136091 | 0.82 | EPHX1 (0.56) | EPHX1EPHX2L3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL22892866 | 0.82 | CCR5 (0.52) | CCR5 | |
| SCHEMBL24744482 | 0.81 | L3MBTL1 (0.62) | EPHX1EPHX2L3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL12482202 | 0.80 | SSTR4 (0.42) | KDM4EALDH1A1 | |
| SCHEMBL8418348 | 0.79 | KDM4E (0.46) | EPHX1EPHX2KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL28861677 | 0.79 | KMT2A (0.43) | KDM4ESMN1; SMN2NPSR1ALDH1A1KMT2A | |
| SCHEMBL21290845 | 0.79 | KDM4E (0.46) | EPHX1EPHX2KDM4ESMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3147279-A1 | CAROTENOID DERIVATIVE, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PHARMACEUTICALLY ACCEPTABLE ESTER OR AMIDE THEREOF | Fuji Chemical Industry Co., Ltd. (JP) | 2017-03-29 | — | — | EP | disclosed |