Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.36 |
| ▸ | MDM4 | O15151 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | BMP1 | P13497 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13227693 | 0.92 | KMT2A (0.45) | KMT2AMEN1POLBMDM2CASP3 | |
| SCHEMBL27214060 | 0.91 | KMT2A (0.54) | KMT2AMEN1POLBMDM2NPC1 | |
| SCHEMBL31749265 | 0.91 | KMT2A (0.54) | KMT2AMEN1POLBMDM2NPC1 | |
| SCHEMBL12200636 | 0.90 | KMT2A (0.43) | KMT2AMEN1POLBMDM2CASP3 | |
| SCHEMBL20586242 | 0.89 | KMT2A (0.48) | KMT2AMEN1POLBMDM2NPC1 | |
| SCHEMBL14007040 | 0.89 | KMT2A (0.51) | KMT2AMEN1POLBMDM2NPC1 | |
| SCHEMBL31146900 | 0.88 | KMT2A (0.45) | KMT2AMEN1MDM2CASP3NPC1 | |
| SCHEMBL3367289 | 0.88 | KMT2A (0.45) | KMT2AMEN1MDM2CASP3NPC1 | |
| SCHEMBL29368397 | 0.88 | KMT2A (0.45) | KMT2AMEN1MDM2CASP3NPC1 | |
| SCHEMBL1745934 | 0.88 | KMT2A (0.45) | KMT2AMEN1MDM2CASP3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7238671-B2 | Human glucagon-like-peptide-1 mimics and their use in the treatment of diabetes and related conditions | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-07-03 | — | — | US | disclosed |