Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.40 |
| ▸ | ADAMTS5 | Q9UNA0 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31749265 | 0.94 | KMT2A (0.54) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL27214060 | 0.94 | KMT2A (0.54) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL14007040 | 0.92 | KMT2A (0.51) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL14450381 | 0.89 | KMT2A (0.46) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL12972568 | 0.89 | MEN1 (0.45) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL13227693 | 0.89 | KMT2A (0.45) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL17190820 | 0.88 | KMT2A (0.45) | KMT2AMEN1MDM2MAPTSMN1; SMN2 | |
| SCHEMBL14123991 | 0.88 | NPC1 (0.44) | KMT2AMEN1NPC1RAB9AMDM2 | |
| SCHEMBL31146900 | 0.88 | KMT2A (0.45) | KMT2AMEN1NPC1RAB9AMDM2 | |
| SCHEMBL29368397 | 0.88 | KMT2A (0.45) | KMT2AMEN1NPC1RAB9AMDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11168114-B2 | Process for the manufacture of degarelix and its intermediates | Fresenius Kabi iPSUM S.r.l (IT) | 2021-11-09 | — | — | US | disclosed |
| US-20200172577-A9 | PROCESS FOR THE MANUFACTURE OF DEGARELIX AND ITS INTERMEDIATES | Fresenius Kabi Ipsum S.R.L. (IT) | 2020-06-04 | — | — | US | disclosed |
| US-20180362588-A1 | PROCESS FOR THE MANUFACTURE OF DEGARELIX AND ITS INTERMEDIATES | FRESENIUS KABI IPSUM S R L (IT) | 2018-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11168114-B2 | Process for the manufacture of degarelix and its intermediates | ANPEP, DNPEP, NPPA | KMT2A 1638/4885MEN1 2301/4885NPC1 3482/4885 |
| US-20200172577-A9 | PROCESS FOR THE MANUFACTURE OF DEGARELIX AND ITS INTERMEDIATES | ANPEP, DNPEP, NPPA | KMT2A 1638/4885MEN1 2301/4885NPC1 3482/4885 |
| US-20180362588-A1 | PROCESS FOR THE MANUFACTURE OF DEGARELIX AND ITS INTERMEDIATES | ANPEP, DNPEP, NPPA | KMT2A 1638/4885MEN1 2301/4885NPC1 3482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.