Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.32 |
| ▸ | AGER | Q15109 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18069556 | 0.83 | FGFR1 (0.50) | MAPTLMNAFGFR1SLC22A6 | |
| SCHEMBL140792 | 0.83 | FGFR1 (0.50) | MAPTLMNAFGFR1SLC22A6 | |
| SCHEMBL14963612 | 0.80 | MAPT (0.47) | TSHRMAPTLMNAHTTALDH1A1 | |
| SCHEMBL27056613 | 0.77 | MEN1 (0.37) | HPGDMAPTALDH1A1KMT2ACSNK2A1 | |
| SCHEMBL27056610 | 0.77 | MEN1 (0.37) | HPGDMAPTALDH1A1KMT2ACSNK2A1 | |
| SCHEMBL2865257 | 0.77 | KMT2A (0.40) | TSHRMAPTLMNAALDH1A1DRD2 | |
| SCHEMBL27059540 | 0.76 | DRD2 (0.34) | MAPTDRD2DRD3KMT2APKM | |
| SCHEMBL25520895 | 0.75 | FGFR1 (0.52) | MAPTLMNAALDH1A1FGFR1KMT2A | |
| SCHEMBL26040211 | 0.72 | PKM (0.62) | LMNAALDH1A1PKML3MBTL1 | |
| SCHEMBL27056608 | 0.72 | KMT2A (0.47) | MAPTLMNAHTTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070167353-A1 | PRODRUG COMPOSITION | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2007-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070167353-A1 | PRODRUG COMPOSITION | ADA, SLC29A1, SLC29A2 | TSHR 4217/4885HPGD 1251/4885MAPT 2338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.