Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 3/20 | 0.52 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TYMP | P19971 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | VCP | P55072 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14450629 | 0.85 | FGFR1 (0.56) | FGFR1SLC22A6PKMTYMPMAPT | |
| SCHEMBL25521527 | 0.85 | FGFR1 (0.71) | FGFR1SLC22A6PKMTYMPMAPT | |
| SCHEMBL15046004 | 0.85 | FGFR1 (0.71) | FGFR1SLC22A6PKMTYMPMAPT | |
| SCHEMBL13799139 | 0.84 | FGFR1 (0.74) | FGFR1SLC22A6PKMTYMPCYP3A4 | |
| SCHEMBL15354006 | 0.77 | FGFR1 (0.62) | FGFR1SLC22A6TYMPCYP3A4HPRT1 | |
| SCHEMBL14450620 | 0.75 | TSHR (0.38) | FGFR1SLC22A6PKMMAPTKMT2A | |
| SCHEMBL13799136 | 0.75 | FGFR1 (0.46) | FGFR1SLC22A6PKMTYMP | |
| SCHEMBL14450632 | 0.75 | FGFR1 (0.44) | FGFR1SLC22A6PKMTYMP | |
| SCHEMBL1105225 | 0.74 | FGFR1 (0.45) | FGFR1SLC22A6TYMPKMT2AMEN1 | |
| SCHEMBL26772786 | 0.73 | FGFR1 (0.65) | FGFR1SLC22A6TYMPCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159574-A1 | BENZYLOXY PHOSPH(ON)ATE COMPOUNDS | CITIBANK, N.A., AS ADMINISTRATIVE AGENT | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159574-A1 | BENZYLOXY PHOSPH(ON)ATE COMPOUNDS | PYGL, GOT2, ALPI | FGFR1 2506/4885SLC22A6 1841/4885PKM 538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.