Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.55 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.55 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.55 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8228179 | 0.88 | ADRB2 (0.77) | MEN1KMT2AKDM4EPOLBADRB2 | |
| SCHEMBL14456710 | 0.85 | ADRB2 (0.67) | MEN1KMT2APOLBADRB2ALDH1A1 | |
| SCHEMBL8228226 | 0.84 | ADRB2 (0.69) | MEN1KMT2APOLBADRB2ALDH1A1 | |
| SCHEMBL14456886 | 0.84 | CYP3A4 (0.69) | MEN1KMT2AKDM4EADRB2ALDH1A1 | |
| SCHEMBL14456716 | 0.83 | ADRB2 (0.59) | MEN1KMT2AKDM4EADRB2ALDH1A1 | |
| SCHEMBL14456766 | 0.82 | CYP3A4 (0.67) | KDM4EALDH1A1TSHRMAPK1MTNR1B | |
| SCHEMBL14456811 | 0.82 | CYP3A4 (0.71) | MEN1KMT2AKDM4EPOLBALDH1A1 | |
| SCHEMBL14456711 | 0.82 | ADRB2 (0.65) | MEN1KMT2AKDM4EPOLBADRB2 | |
| SCHEMBL8223186 | 0.82 | ADRB2 (0.62) | MEN1KMT2AADRB2ALDH1A1TSHR | |
| SCHEMBL14456712 | 0.82 | ALDH1A1 (0.79) | MEN1KMT2APOLBADRB2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7238688-B2 | Piperidine compounds | SCHERING CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |
| US-7238688-B2 | Piperidine compounds | SCHERING CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |