Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.59 |
| ▸ | FAAH | O00519 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.53 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.53 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.53 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.53 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8228179 | 0.86 | ADRB2 (0.77) | ADRB2FAAHTSHRMEN1KMT2A | |
| SCHEMBL8228226 | 0.85 | ADRB2 (0.69) | ADRB2FAAHTSHRMEN1KMT2A | |
| SCHEMBL14456710 | 0.84 | ADRB2 (0.67) | ADRB2FAAHTSHRMEN1KMT2A | |
| SCHEMBL8223191 | 0.84 | FAAH (0.82) | ADRB2FAAHTSHRSMN1; SMN2MAPT | |
| SCHEMBL14456715 | 0.83 | MEN1 (0.69) | ADRB2TSHRMEN1KMT2AMAPK1 | |
| SCHEMBL14456742 | 0.83 | MEN1 (0.60) | TSHRMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL14456886 | 0.82 | CYP3A4 (0.69) | ADRB2TSHRMEN1KMT2AMAPK1 | |
| SCHEMBL14456711 | 0.80 | ADRB2 (0.65) | ADRB2FAAHTSHRMEN1KMT2A | |
| SCHEMBL8223186 | 0.80 | ADRB2 (0.62) | ADRB2TSHRMEN1KMT2AMAPK1 | |
| SCHEMBL14456712 | 0.80 | ALDH1A1 (0.79) | ADRB2TSHRMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7238688-B2 | Piperidine compounds | SCHERING CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |
| US-7238688-B2 | Piperidine compounds | SCHERING CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |