Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14456768 | 0.87 | KDM4E (0.66) | CYP3A4CYP2D6KDM4EALDH1A1HTT | |
| SCHEMBL14456774 | 0.87 | CYP3A4 (0.54) | CYP3A4CYP2D6MEN1TSHRKMT2A | |
| SCHEMBL14456796 | 0.86 | KDM4E (0.52) | CYP3A4CYP2D6MEN1TSHRKMT2A | |
| SCHEMBL14456781 | 0.85 | TP53 (0.56) | CYP3A4CYP2D6KMT2AKDM4EALDH1A1 | |
| SCHEMBL14456827 | 0.83 | CYP3A4 (0.68) | CYP3A4CYP2D6MEN1TSHRKMT2A | |
| SCHEMBL14456812 | 0.82 | CYP3A4 (0.56) | CYP3A4CYP2D6MEN1KMT2AKDM4E | |
| SCHEMBL14456828 | 0.82 | MEN1 (0.66) | CYP3A4CYP2D6MEN1TSHRKMT2A | |
| SCHEMBL14456748 | 0.82 | KMT2A (0.73) | CYP3A4CYP2D6MEN1TSHRKMT2A | |
| SCHEMBL14456892 | 0.82 | MEN1 (0.63) | CYP3A4CYP2D6MEN1TSHRKMT2A | |
| SCHEMBL14456744 | 0.81 | KMT2A (0.56) | CYP3A4CYP2D6MEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7238688-B2 | Piperidine compounds | SCHERING CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |
| US-7238688-B2 | Piperidine compounds | SCHERING CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |