Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.54 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14456781 | 0.89 | TP53 (0.56) | CYP3A4CYP2D6KDM4EALDH1A1KMT2A | |
| SCHEMBL14456776 | 0.88 | KDM4E (0.70) | CYP3A4CYP2D6KDM4EALDH1A1LMNA | |
| SCHEMBL14456811 | 0.87 | CYP3A4 (0.71) | CYP3A4CYP2D6KDM4EALDH1A1MEN1 | |
| SCHEMBL8223176 | 0.86 | CCR8 (0.60) | CYP3A4CYP2D6KDM4EALDH1A1LMNA | |
| SCHEMBL14456739 | 0.86 | CCR8 (0.60) | CYP3A4CYP2D6KDM4EALDH1A1LMNA | |
| SCHEMBL14456817 | 0.83 | FAAH (0.69) | — | |
| SCHEMBL14456824 | 0.83 | FAAH (0.58) | CYP3A4CYP2D6KDM4EALDH1A1LMNA | |
| SCHEMBL14456779 | 0.82 | CYP3A4 (0.51) | CYP3A4CYP2D6KDM4EALDH1A1HTT | |
| SCHEMBL14456753 | 0.82 | MEN1 (0.57) | CYP3A4CYP2D6ALDH1A1MEN1KMT2A | |
| SCHEMBL14456886 | 0.82 | CYP3A4 (0.69) | CYP3A4CYP2D6KDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7238688-B2 | Piperidine compounds | SCHERING CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |
| US-7238688-B2 | Piperidine compounds | SCHERING CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |