Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14456768 | 0.88 | KDM4E (0.66) | KDM4EALDH1A1HTTCYP3A4CYP2D6 | |
| SCHEMBL14456779 | 0.86 | CYP3A4 (0.51) | KDM4EALDH1A1HTTCYP3A4CYP2D6 | |
| SCHEMBL14456774 | 0.84 | CYP3A4 (0.54) | KDM4EALDH1A1HTTCYP3A4CYP2D6 | |
| SCHEMBL14456836 | 0.81 | CYP3A4 (0.57) | ALDH1A1CYP3A4CYP2D6MEN1TSHR | |
| SCHEMBL14456827 | 0.81 | CYP3A4 (0.68) | ALDH1A1CYP3A4CYP2D6MEN1TSHR | |
| SCHEMBL14456828 | 0.80 | MEN1 (0.66) | ALDH1A1CYP3A4CYP2D6MEN1TSHR | |
| SCHEMBL14469114 | 0.80 | RAB9A (0.41) | KDM4EALDH1A1HTTMEN1KMT2A | |
| SCHEMBL14456748 | 0.80 | KMT2A (0.73) | KDM4EALDH1A1CYP3A4CYP2D6MEN1 | |
| SCHEMBL14456892 | 0.79 | MEN1 (0.63) | ALDH1A1CYP3A4CYP2D6MEN1TSHR | |
| SCHEMBL14456772 | 0.79 | ALDH1A1 (0.56) | KDM4EALDH1A1HTTCYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7238688-B2 | Piperidine compounds | SCHERING CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |
| US-7238688-B2 | Piperidine compounds | SCHERING CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |