Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CCR8 | P51685 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14456824 | 0.90 | FAAH (0.58) | FAAHCYP3A4CYP2D6CCR8KDM4E | |
| SCHEMBL14456739 | 0.90 | CCR8 (0.60) | FAAHCYP3A4CYP2D6CCR8KDM4E | |
| SCHEMBL8223176 | 0.90 | CCR8 (0.60) | FAAHCYP3A4CYP2D6CCR8KDM4E | |
| SCHEMBL14456817 | 0.89 | FAAH (0.69) | FAAH | |
| SCHEMBL14456822 | 0.86 | FAAH (0.59) | FAAHCYP3A4CYP2D6KDM4EPOLB | |
| SCHEMBL14456829 | 0.86 | L3MBTL1 (0.56) | CYP3A4CYP2D6 | |
| SCHEMBL14456811 | 0.85 | CYP3A4 (0.71) | CYP3A4CYP2D6KDM4EPOLB | |
| SCHEMBL14456815 | 0.84 | TP53 (0.60) | FAAHCYP3A4CYP2D6 | |
| SCHEMBL14469470 | 0.82 | FAAH (0.52) | FAAHCYP3A4CYP2D6CCR8KDM4E | |
| SCHEMBL14456776 | 0.81 | KDM4E (0.70) | FAAHCYP3A4CYP2D6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7238688-B2 | Piperidine compounds | SCHERING CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |
| US-7238688-B2 | Piperidine compounds | SCHERING CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |