Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.53 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.53 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14456800 | 0.92 | ALDH1A2 (0.61) | FAAHCYP3A4CYP2D6ALDH1A2ALDH1A1 | |
| SCHEMBL8223176 | 0.89 | CCR8 (0.60) | FAAHCYP3A4CYP2D6ALDH1A1KDM4E | |
| SCHEMBL14456739 | 0.89 | CCR8 (0.60) | FAAHCYP3A4CYP2D6ALDH1A1KDM4E | |
| SCHEMBL14456818 | 0.86 | FAAH (0.60) | FAAHCYP3A4CYP2D6KDM4EPOLB | |
| SCHEMBL14456817 | 0.86 | FAAH (0.69) | FAAH | |
| SCHEMBL14456824 | 0.85 | FAAH (0.58) | FAAHCYP3A4CYP2D6ALDH1A1KDM4E | |
| SCHEMBL14456811 | 0.84 | CYP3A4 (0.71) | CYP3A4CYP2D6ALDH1A1KDM4EPOLB | |
| SCHEMBL14456891 | 0.83 | HIF1A (0.60) | CYP3A4POLB | |
| SCHEMBL14469472 | 0.82 | FAAH (0.51) | FAAHALDH1A2ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL14456812 | 0.81 | CYP3A4 (0.56) | CYP3A4CYP2D6ALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7238688-B2 | Piperidine compounds | SCHERING CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |
| US-7238688-B2 | Piperidine compounds | SCHERING CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |