Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14456938 | 0.84 | CYP3A4 (0.51) | TBK1CYP3A4 | |
| SCHEMBL13003343 | 0.81 | CYP3A4 (0.53) | TBK1CYP3A4 | |
| SCHEMBL14456932 | 0.80 | MEN1 (0.57) | TBK1CYP3A4ALDH1A1SMN1; SMN2 | |
| SCHEMBL14456931 | 0.80 | MEN1 (0.55) | CYP3A4ALDH1A1SMN1; SMN2 | |
| SCHEMBL18985960 | 0.80 | TBK1 (0.60) | TBK1CYP3A4 | |
| SCHEMBL13391188 | 0.80 | CYP3A4 (0.55) | CYP3A4 | |
| SCHEMBL14456908 | 0.80 | CYP3A4 (0.54) | TBK1CYP3A4 | |
| SCHEMBL14456923 | 0.79 | MEN1 (0.56) | CYP3A4ALDH1A1SMN1; SMN2 | |
| SCHEMBL14456951 | 0.79 | L3MBTL1 (0.56) | TBK1CYP3A4ALDH1A1 | |
| SCHEMBL14456964 | 0.79 | CNR1 (0.60) | CYP3A4ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7238688-B2 | Piperidine compounds | SCHERING CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |
| US-7238688-B2 | Piperidine compounds | SCHERING CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |