Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14456929 | 0.91 | MEN1 (0.51) | CYP3A4MEN1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL14456936 | 0.84 | MEN1 (0.47) | CYP3A4MEN1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL14456938 | 0.81 | CYP3A4 (0.51) | CYP3A4 | |
| SCHEMBL14456908 | 0.80 | CYP3A4 (0.54) | CYP3A4 | |
| SCHEMBL18985960 | 0.79 | TBK1 (0.60) | CYP3A4 | |
| SCHEMBL14456915 | 0.79 | CYP3A4 (0.57) | CYP3A4 | |
| SCHEMBL14456933 | 0.76 | CYP3A4 (0.55) | CYP3A4SMN1; SMN2 | |
| SCHEMBL14456948 | 0.76 | ALDH1A1 (0.52) | CYP3A4 | |
| SCHEMBL14456951 | 0.76 | L3MBTL1 (0.56) | CYP3A4L3MBTL1 | |
| SCHEMBL14456916 | 0.76 | CYP3A4 (0.60) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075555-A2 | COMBINATION OF AN H3 ANTAGONIST/INVERSE AGONIST AND AN APPETITE SUPPRESSANT | SCHERING CORPORATION (US) | 2007-07-05 | — | — | WO | disclosed |