Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8418299 | 0.89 | CYP3A4 (0.55) | CYP3A4 | |
| SCHEMBL14456997 | 0.89 | CYP3A4 (0.50) | CYP3A4ALDH1A1 | |
| SCHEMBL14456935 | 0.88 | CYP3A4 (0.46) | CYP3A4ALDH1A1 | |
| SCHEMBL14456949 | 0.86 | CYP3A4 (0.51) | CYP3A4MEN1KMT2AALDH1A1 | |
| SCHEMBL14456948 | 0.86 | ALDH1A1 (0.52) | CYP3A4ALDH1A1 | |
| SCHEMBL14456946 | 0.85 | CYP3A4 (0.48) | CYP3A4 | |
| SCHEMBL14456910 | 0.84 | CYP3A4 (0.54) | CYP3A4MEN1KMT2A | |
| SCHEMBL14456965 | 0.83 | CYP3A4 (0.52) | CYP3A4 | |
| SCHEMBL14456909 | 0.83 | CYP3A4 (0.53) | CYP3A4MEN1KMT2A | |
| SCHEMBL14456996 | 0.81 | POLB (0.51) | CYP3A4KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7238688-B2 | Piperidine compounds | SCHERING CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |
| US-7238688-B2 | Piperidine compounds | SCHERING CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |