Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14456996 | 0.91 | POLB (0.51) | ALDH1A1TSHRPOLBCYP3A4LMNA | |
| SCHEMBL14456935 | 0.86 | CYP3A4 (0.46) | ALDH1A1POLBCYP3A4 | |
| SCHEMBL14456945 | 0.86 | CYP3A4 (0.49) | ALDH1A1CYP3A4 | |
| SCHEMBL13391662 | 0.85 | CYP3A4 (0.45) | ALDH1A1TSHRCYP3A4 | |
| SCHEMBL14456965 | 0.84 | CYP3A4 (0.52) | CYP3A4 | |
| SCHEMBL14456997 | 0.83 | CYP3A4 (0.50) | ALDH1A1TSHRPOLBCYP3A4LMNA | |
| SCHEMBL8418299 | 0.82 | CYP3A4 (0.55) | CYP3A4 | |
| SCHEMBL18985960 | 0.81 | TBK1 (0.60) | CYP3A4TBK1 | |
| SCHEMBL14456986 | 0.81 | POLB (0.55) | ALDH1A1TSHRPOLBCYP3A4LMNA | |
| SCHEMBL14456908 | 0.81 | CYP3A4 (0.54) | CYP3A4TBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7238688-B2 | Piperidine compounds | SCHERING CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |
| US-7238688-B2 | Piperidine compounds | SCHERING CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |