Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | F10 | P00742 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | LSS | P48449 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14456968 | 0.87 | CNR1 (0.58) | CNR1NPSR1F10GAALSS | |
| SCHEMBL14356016 | 0.81 | MGLL (0.52) | GAA | |
| SCHEMBL13391737 | 0.81 | MGLL (0.52) | GAA | |
| SCHEMBL14456961 | 0.81 | LSS (0.46) | F10LSSALDH1A1L3MBTL1 | |
| SCHEMBL14456956 | 0.81 | CNR1 (0.69) | CNR1NPSR1F10GAALSS | |
| SCHEMBL1387325 | 0.80 | F10 (0.77) | CNR1NPSR1F10GAALSS | |
| SCHEMBL14456971 | 0.77 | HTT (0.51) | CNR1NPSR1F10LSSALDH1A1 | |
| SCHEMBL14469584 | 0.75 | CNR1 (0.57) | CNR1NPSR1F10GAAALDH1A1 | |
| SCHEMBL6180071 | 0.75 | LSS (0.75) | CNR1NPSR1F10GAALSS | |
| SCHEMBL6981670 | 0.74 | LSS (0.76) | CNR1NPSR1F10GAALSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075555-A2 | COMBINATION OF AN H3 ANTAGONIST/INVERSE AGONIST AND AN APPETITE SUPPRESSANT | SCHERING CORPORATION (US) | 2007-07-05 | — | — | WO | disclosed |
| US-7238688-B2 | Piperidine compounds | SCHERING CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |
| US-7238688-B2 | Piperidine compounds | SCHERING CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |