Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | F13A1 | P00488 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | TGM1 | P22735 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14469579 | 0.90 | CNR1 (0.46) | CNR1NPSR1ALDH1A1F10MEN1 | |
| SCHEMBL14469593 | 0.89 | CNR1 (0.45) | CNR1NPSR1GAAALDH1A1KMT2A | |
| SCHEMBL14469366 | 0.81 | CNR1 (0.58) | CNR1NPSR1GAAALDH1A1PKM | |
| SCHEMBL14456962 | 0.75 | CNR1 (0.65) | CNR1NPSR1GAAALDH1A1PKM | |
| SCHEMBL14469581 | 0.74 | ALDH1A1 (0.45) | CNR1NPSR1GAAALDH1A1PKM | |
| SCHEMBL14469240 | 0.73 | CNR1 (0.58) | CNR1NPSR1GAAF10MEN1 | |
| SCHEMBL14469583 | 0.72 | POLB (0.53) | CNR1NPSR1GAAALDH1A1PKM | |
| SCHEMBL14469582 | 0.72 | CNR1 (0.47) | CNR1NPSR1F10 | |
| SCHEMBL14456968 | 0.71 | CNR1 (0.58) | CNR1NPSR1GAAALDH1A1PKM | |
| SCHEMBL14469235 | 0.71 | CNR1 (0.45) | CNR1NPSR1GAAALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075555-A2 | COMBINATION OF AN H3 ANTAGONIST/INVERSE AGONIST AND AN APPETITE SUPPRESSANT | SCHERING CORPORATION (US) | 2007-07-05 | — | — | WO | disclosed |