Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | SORD | Q00796 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14456969 | 0.86 | TBK1 (0.41) | ALDH1A1L3MBTL1SORD | |
| SCHEMBL14456962 | 0.81 | CNR1 (0.65) | LSSALDH1A1L3MBTL1F10 | |
| SCHEMBL14456954 | 0.79 | ALDH1A1 (0.55) | ALDH1A1POLB | |
| SCHEMBL14515115 | 0.74 | LTA4H (0.52) | ALDH1A1ITGB3ITGA2BHPGD | |
| SCHEMBL13391737 | 0.74 | MGLL (0.52) | POLB | |
| SCHEMBL14356016 | 0.74 | MGLL (0.52) | POLB | |
| SCHEMBL13003540 | 0.73 | KDM4D (0.48) | ALDH1A1ITGB3ITGA2B | |
| SCHEMBL14456699 | 0.73 | ACKR3 (0.44) | — | |
| SCHEMBL14456704 | 0.72 | KDM4E (0.48) | ALDH1A1HPGD | |
| SCHEMBL8225769 | 0.72 | KDM4D (0.50) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7238688-B2 | Piperidine compounds | SCHERING CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |
| US-7238688-B2 | Piperidine compounds | SCHERING CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |