Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14456974 | 0.87 | CYP3A4 (0.53) | CYP3A4POLBALDH1A1LMNATSHR | |
| SCHEMBL14456988 | 0.87 | CYP3A4 (0.54) | CYP3A4POLBTSHR | |
| SCHEMBL13003946 | 0.87 | CYP3A4 (0.55) | CYP3A4 | |
| SCHEMBL14457006 | 0.86 | POLB (0.48) | POLBALDH1A1LMNATSHR | |
| SCHEMBL14456999 | 0.85 | CYP3A4 (0.52) | CYP3A4POLBALDH1A1LMNATSHR | |
| SCHEMBL14457001 | 0.85 | ALDH1A1 (0.54) | CYP3A4POLBALDH1A1 | |
| SCHEMBL14456987 | 0.85 | CYP3A4 (0.61) | CYP3A4POLBLMNA | |
| SCHEMBL14456986 | 0.84 | POLB (0.55) | CYP3A4POLBALDH1A1LMNATSHR | |
| SCHEMBL14456951 | 0.84 | L3MBTL1 (0.56) | CYP3A4ALDH1A1 | |
| SCHEMBL14457004 | 0.83 | ALDH1A1 (0.54) | CYP3A4POLBALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7238688-B2 | Piperidine compounds | SCHERING CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |
| US-7238688-B2 | Piperidine compounds | SCHERING CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |