SCHEMBL1445913

SCHEMBL1445913

Fc1cccc([Mg]Cl)c1F

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.38
CES1 P23141 2/20 0.38
BCHE P06276 1/20 0.38
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31
TAAR1 Q96RJ0 1/20 0.30
PKM P14618 1/20 0.30
PKLR P30613 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6986820 0.79
Hydrochloric Acid SCHEMBL11402787 0.77 ACHE (0.36) CES2CES1TAAR1
SCHEMBL5645077 0.76 ACHE (0.37) CES2CES1TAAR1
Bromide SCHEMBL1446078 0.75 CES2 (0.38) CES2CES1BCHESLC6A2SLC6A4
SCHEMBL1162776 0.75 CES2 (0.38) CES2CES1BCHESLC6A2SLC6A4
SCHEMBL31444457 0.75 CES2 (0.38) CES2CES1BCHESLC6A2SLC6A4
Bromide SCHEMBL1445756 0.73 CES2 (0.37) CES2CES1BCHE
SCHEMBL180426 0.71
SCHEMBL17628505 0.70 CES2 (0.36) CES2CES1BCHETAAR1
SCHEMBL1445753 0.69 CES2 (0.30) CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8609574-B2 In situ olefin polymerization catalyst system PROMERUS LLC (US) 2013-12-17 US claimed
EP-2296811-A2 IN SITU OLEFIN POLYMERIZATION CATALYST SYSTEM Promerus, LLC (US) 2011-03-23 EP claimed
US-20090270247-A1 IN SITU OLEFIN POLYMERIZATION CATALYST SYSTEM PROMERUS LLC (US) 2009-10-29 US claimed
WO-2009132240-A2 IN SITU OLEFIN POLYMERIZATION CATALYST SYSTEM PROMERUS LLC (US) 2009-10-29 WO claimed
US-8609574-B2 In situ olefin polymerization catalyst system PROMERUS LLC (US) 2013-12-17 US disclosed
EP-2296811-A2 IN SITU OLEFIN POLYMERIZATION CATALYST SYSTEM Promerus, LLC (US) 2011-03-23 EP disclosed
US-20090270247-A1 IN SITU OLEFIN POLYMERIZATION CATALYST SYSTEM PROMERUS LLC (US) 2009-10-29 US disclosed
WO-2009132240-A2 IN SITU OLEFIN POLYMERIZATION CATALYST SYSTEM PROMERUS LLC (US) 2009-10-29 WO disclosed