Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 15/20 | 0.65 |
| ▸ | FLT1 | P17948 | 1/20 | 0.65 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL903605 | 0.87 | AHR (0.46) | AHRFLT1CYP2A6POLBCASP6 | |
| SCHEMBL16779994 | 0.87 | AHR (0.46) | AHRFLT1CYP2A6POLBCASP6 | |
| 2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL10692053 | 0.84 | AHR (0.72) | AHRFLT1 | |
| SCHEMBL3096913 | 0.84 | AHR (0.72) | AHRFLT1 | |
| SCHEMBL14458072 | 0.81 | AHR (0.54) | AHRCYP2A6POLBCASP6MAPT | |
| 2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL10906041 | 0.81 | AHR (0.87) | AHRFLT1 | |
| 2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL8939 | 0.81 | AHR (1.00) | AHRFLT1 | |
| 2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL29350382 | 0.81 | AHR (1.00) | AHRFLT1 | |
| 2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL29364019 | 0.81 | AHR (1.00) | AHRFLT1 | |
| 2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL1747904 | 0.80 | AHR (0.65) | AHRFLT1CYP2A6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241905-B2 | Dioxin analogues and methods and kits for searching out dioxins-decomposing organisms or enzymes or dioxin-decomposing enzyme genes | FORESTRY AND FOREST PRODUCTS RESEARCH INSTITUTE (JP) | 2007-07-10 | — | — | US | disclosed |
| US-7241905-B2 | Dioxin analogues and methods and kits for searching out dioxins-decomposing organisms or enzymes or dioxin-decomposing enzyme genes | FORESTRY AND FOREST PRODUCTS RESEARCH INSTITUTE (JP) | 2007-07-10 | — | — | US | disclosed |