2,3,7,8-Tetrachlorodibenzo-P-Dioxin

SCHEMBL10692053

Clc1cc2c(cc1Cl)Oc1cc(Cl)c(Cl)cc1O2.c1ccc2c(c1)Oc1ccccc1O2

nearest known ligand 0.72

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	AHR	P35869	16/20	0.72

▸	FLT1	P17948	1/20	0.72

▸	LMNA	P02545	1/20	0.40

▸	TSHR	P16473	1/20	0.40

▸	ALOX5	P09917	1/20	0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL3096913	1.00	AHR (0.72)	AHRFLT1LMNATSHRALOX5
2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL10906041	0.85	AHR (0.87)	AHRFLT1
2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL8939	0.85	AHR (1.00)	AHRFLT1
2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL29364019	0.85	AHR (1.00)	AHRFLT1
2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL29350382	0.85	AHR (1.00)	AHRFLT1
2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL1747904	0.84	AHR (0.65)	AHRFLT1
SCHEMBL14458065	0.84	AHR (0.65)	AHRFLT1
2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL7544600	0.82	AHR (0.93)	AHRFLT1
2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL1837452	0.82	AHR (0.93)	AHRFLT1
2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL8815834	0.82	AHR (0.93)	AHRFLT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0259073-A2	Antibody-based bioassays for enzyme-inducing chemicals	WESTINGHOUSE ELECTRIC CORPORATION (US)	1988-03-09	—	—	EP	claimed