2,3,7,8-Tetrachlorodibenzo-P-Dioxin

2,3,7,8-Tetrachlorodibenzo-P-Dioxin

SCHEMBL1747904

Clc1cc2c(cc1Cl)Oc1cc(Cl)c(Cl)cc1O2.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
AHR P35869 13/20 0.65
FLT1 P17948 1/20 0.65
CYP1A2 P05177 1/20 0.46
ALDH1A1 P00352 1/20 0.45
ESR2 Q92731 1/20 0.45
CYP2A6 P11509 1/20 0.42
MEN1 O00255 1/20 0.39
HSP90AA1 P07900 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL10906041 0.87 AHR (0.87) AHRFLT1
2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL10692053 0.84 AHR (0.72) AHRFLT1
SCHEMBL3096913 0.84 AHR (0.72) AHRFLT1
2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL7159644 0.81 AHR (0.59) AHRFLT1ALDH1A1MEN1KMT2A
2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL29350382 0.81 AHR (1.00) AHRFLT1
2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL8939 0.81 AHR (1.00) AHRFLT1
2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL29364019 0.81 AHR (1.00) AHRFLT1
SCHEMBL14458065 0.80 AHR (0.65) AHRFLT1CYP1A2CYP2A6
2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL14941758 0.79 AHR (0.56) AHRFLT1CYP1A2ALDH1A1CYP2A6
2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL7544600 0.78 AHR (0.93) AHRFLT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115612176-A Reactive flame retardant containing DOPO group and nitrogen-containing heterocycle and preparation method and application thereof 浙江工业大学 2023-01-17 CN disclosed
CN-113956830-A Polyurethane pouring sealant and preparation method thereof 醴陵市京渌新材料有限公司 2022-01-21 CN disclosed
CN-112023914-A Dioxin removal catalyst for incineration fly ash desorption treatment and preparation method thereof 广州维港环保科技有限公司 2020-12-04 CN disclosed
US-20190336937-A1 TREATMENTS FOR PERSISTENT ORGANIC POLLUTANTS VIROTEC PTY LTD (AU) 2019-11-07 US disclosed
US-7902262-B2 Method of recycling mixed streams of ewaste (WEEE) CLOSE THE LOOP TECHNOLOGIES PTY LTD. (AU) 2011-03-08 US disclosed
EP-1773923-A4 A METHOD OF RECYCLING MIXED STREAMS OF EWASTE (WEEE) CLOSE THE LOOP TECHNOLOGIES PT (AU) 2008-06-25 EP disclosed
EP-1773923-A1 A METHOD OF RECYCLING MIXED STREAMS OF EWASTE (WEEE) Close the Loop Technologies Pty Ltd (AU) 2007-04-18 EP disclosed
US-20070054106-A1 Method of recycling mixed streams of ewaste (weee) CLOSE THE LOOP TECHNOLOGIES PTY LTD. (AU) 2007-03-08 US disclosed
WO-2005123817-A1 A METHOD OF RECYCLING MIXED STREAMS OF EWASTE (WEEE) CLOSE THE LOOP TECHNOLOGIES PTY LTD (AU) 2005-12-29 WO disclosed