Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14284230 | 0.73 | LMNA (0.44) | LMNAMAPTTDP1CYP3A4HTT | |
| SCHEMBL14458095 | 0.71 | PDE4D (0.50) | LMNASMN1; SMN2GAAKCNA3 | |
| SCHEMBL18860720 | 0.70 | ALDH1A1 (0.44) | LMNAMAPTSMN1; SMN2 | |
| SCHEMBL15373320 | 0.69 | BCHE (0.41) | LMNAMAPTTDP1SMN1; SMN2 | |
| SCHEMBL20855865 | 0.69 | HCRTR1 (0.42) | LMNAMAPTCYP3A4HTTCA9 | |
| SCHEMBL23267686 | 0.69 | LMNA (0.40) | LMNAMAPTCYP3A4HTTSMN1; SMN2 | |
| SCHEMBL18864947 | 0.69 | CYP3A4 (0.47) | LMNAMAPTCYP3A4HTTSMN1; SMN2 | |
| SCHEMBL12829101 | 0.69 | DYRK1A (0.39) | — | |
| SCHEMBL21605545 | 0.68 | MAPT (0.40) | LMNAMAPTHTTSMN1; SMN2MAPK1 | |
| SCHEMBL19196784 | 0.68 | ALDH1A1 (0.46) | LMNAMAPTHTTSMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7250389-B1 | Antifungal compound and process for producing the same | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-07-31 | — | — | US | disclosed |
| US-7250389-B1 | Antifungal compound and process for producing the same | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-07-31 | — | — | US | disclosed |