Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.40 |
| ▸ | ALPG | P10696 | 2/20 | 0.39 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31590567 | 0.89 | ALDH1A1 (0.47) | KCNH2ALDH1A1POLBKMT2ATLR8 | |
| SCHEMBL20425451 | 0.86 | KCNH2 (0.42) | KCNH2ALPGPLAAALPL | |
| SCHEMBL4227889 | 0.86 | ALDH1A1 (0.46) | KCNH2ALDH1A1POLBKMT2ATLR8 | |
| SCHEMBL216892 | 0.86 | TLR8 (0.46) | KCNH2ALDH1A1POLBKMT2ATLR8 | |
| SCHEMBL218249 | 0.86 | TLR8 (0.46) | KCNH2ALDH1A1POLBKMT2ATLR8 | |
| SCHEMBL29138650 | 0.86 | TLR8 (0.46) | KCNH2ALDH1A1POLBKMT2ATLR8 | |
| SCHEMBL14921056 | 0.86 | TLR8 (0.46) | KCNH2ALDH1A1POLBKMT2ATLR8 | |
| SCHEMBL9979698 | 0.86 | TLR8 (0.46) | KCNH2ALDH1A1POLBKMT2ATLR8 | |
| SCHEMBL9408468 | 0.86 | TLR8 (0.46) | KCNH2ALDH1A1POLBKMT2ATLR8 | |
| SCHEMBL18339282 | 0.86 | TLR8 (0.46) | KCNH2ALDH1A1POLBKMT2ATLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2773378-B1 | PRODRUGS OF NON-STEROID ANTI-INFLAMMATORY AGENTS (NSAIDS) | SELCH LARSEN CLAUS (DK) | 2016-08-10 | — | — | EP | claimed |
| EP-3511003-A1 | CYCLIC AMINE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | Toray Industries, Inc. (JP) | 2019-07-17 | — | — | EP | disclosed |
| US-9809557-B2 | Prodrugs of non-steroid anti-inflammatory agents (NSAIDS) | SELCH LARSEN CLAUS (DK) | 2017-11-07 | — | — | US | disclosed |
| US-9809557-B2 | Prodrugs of non-steroid anti-inflammatory agents (NSAIDS) | SELCH LARSEN CLAUS (DK) | 2017-11-07 | — | — | US | disclosed |
| US-20140315960-A1 | PRODRUGS OF NON-STEROID ANTI-INFLAMMATORY AGENTS (NSAIDS) | SELCH LARSEN CLAUS (DK) | 2014-10-23 | — | — | US | disclosed |
| US-20140315960-A1 | PRODRUGS OF NON-STEROID ANTI-INFLAMMATORY AGENTS (NSAIDS) | SELCH LARSEN CLAUS (DK) | 2014-10-23 | — | — | US | disclosed |
| EP-0049913-A2 | New ethenylimidazole derivatives, processes for their preparation and pharmaceutical compositions containing them; intermediates, useful in their preparation and a process for the preparation thereof | GIST-BROCADES N.V. (NL) | 1982-04-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140315960-A1 | PRODRUGS OF NON-STEROID ANTI-INFLAMMATORY AGENTS (NSAIDS) | MMP1, MIF, CYP21A2 | KCNH2 4085/4885ALDH1A1 406/4885POLB 4171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.