Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14463092 | 0.83 | PTGS2 (0.36) | MAOAMAOBMEN1KMT2ALMNA | |
| SCHEMBL14017872 | 0.83 | BRD4 (0.39) | BRD4RECQLMAOAMAOBMEN1 | |
| SCHEMBL14462538 | 0.81 | DDB1 (0.38) | CYP3A4CYP2C9CYP2C19MAOAMAOB | |
| SCHEMBL14462492 | 0.81 | LMNA (0.44) | BRD4GAACYP2C9CYP2C19RECQL | |
| SCHEMBL14462487 | 0.81 | DDB1 (0.38) | GAAMEN1KMT2ALMNAKDM4E | |
| SCHEMBL14462535 | 0.80 | CYP1A2 (0.39) | MAOAMAOBDDB1CRBNTYMS | |
| SCHEMBL14462643 | 0.78 | HPGD (0.40) | AKR1C3AKR1C1BRD4MAPK14GAA | |
| SCHEMBL14462541 | 0.75 | DYRK1A (0.37) | BRD4MAPK14MAOAMAOBLMNA | |
| SCHEMBL14462497 | 0.74 | DDB1 (0.40) | MEN1KMT2ALMNAKDM4EMAPT | |
| SCHEMBL14463001 | 0.74 | LDHA (0.40) | BRD4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301492-B1 | NOVEL TETRAZOLE DERIVATIVES | BAYER CROPSCIENCE KK (JP) | 2007-07-04 | — | — | EP | disclosed |