Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 9/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14463390 | 0.92 | KMT2A (0.49) | KMT2ANPC1RAB9AMEN1MAPT | |
| SCHEMBL14463391 | 0.88 | KMT2A (0.45) | KMT2ANPC1RAB9AMEN1MAPT | |
| SCHEMBL14463843 | 0.88 | MAPT (0.57) | KMT2ANPC1RAB9AMAPTMAPK1 | |
| SCHEMBL14463859 | 0.85 | AR (0.43) | KMT2ANPC1RAB9AMEN1MAPT | |
| SCHEMBL4932353 | 0.82 | MEN1 (0.60) | KMT2ANPC1RAB9AMEN1MAPT | |
| SCHEMBL14463461 | 0.81 | MAPT (0.54) | KMT2ANPC1RAB9AMEN1MAPT | |
| SCHEMBL8886349 | 0.81 | MAPT (0.59) | KMT2ANPC1RAB9AMEN1MAPT | |
| SCHEMBL14463840 | 0.81 | KMT2A (0.58) | KMT2ANPC1RAB9AMEN1MAPT | |
| SCHEMBL18296772 | 0.80 | L3MBTL1 (0.59) | KMT2AMEN1MAPTMAPK1ALDH1A1 | |
| SCHEMBL7975715 | 0.80 | RAB9A (0.56) | KMT2ANPC1RAB9AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1810677-A1 | RECEPTOR FUNCTION REGULATING AGENT | Takeda Pharmaceutical Company Limited (JP) | 2007-07-25 | — | — | EP | disclosed |