Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 3/20 | 0.42 |
| ▸ | PDE2A | O00408 | 2/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14463731 | 0.93 | CDK2 (0.42) | CDK2PDE2ACSNK2A1KDM4EGABRA1 | |
| SCHEMBL4507666 | 0.86 | GSK3B (0.36) | CDK2MAPKAPK2CNR1CNR2 | |
| SCHEMBL14340722 | 0.85 | KDM4E (0.42) | CDK2PDE2ACSNK2A1KDM4EGABRA1 | |
| SCHEMBL4692686 | 0.83 | SCN10A (0.31) | — | |
| SCHEMBL4693069 | 0.82 | PDE2A (0.41) | CDK2PDE2ACSNK2A1KDM4EGABRA1 | |
| SCHEMBL13606351 | 0.82 | JAK2 (0.43) | KDM4EALDH1A1HPGDMAPK1HSD17B10 | |
| SCHEMBL4499049 | 0.82 | SCN10A (0.33) | — | |
| SCHEMBL4489875 | 0.82 | ADAM17 (0.32) | — | |
| SCHEMBL13606354 | 0.81 | ALDH1A1 (0.37) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL13606357 | 0.80 | JAK2 (0.35) | KDM4EALDH1A1HPGDHSD17B10JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1694681-B1 | PYRAZOLOPYRIMIDINES | BAYER CROPSCIENCE AG (DE) | 2008-03-12 | — | — | EP | disclosed |
| EP-1697372-B1 | PYRAZOLOPYRIMIDINES | BAYER CROPSCIENCE AG (DE) | 2007-12-19 | — | — | EP | disclosed |
| US-20070259893-A1 | microbicides, fungicides; 7-amino-pyrazolo(1,5-a)pyrimidines; controlling unwanted microorganisms | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-11-08 | — | — | US | disclosed |
| US-20070259893-A1 | microbicides, fungicides; 7-amino-pyrazolo(1,5-a)pyrimidines; controlling unwanted microorganisms | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-11-08 | — | — | US | disclosed |
| US-20070197540-A1 | Pyrazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2007-08-23 | — | — | US | disclosed |
| US-20070197540-A1 | Pyrazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2007-08-23 | — | — | US | disclosed |
| US-20070197540-A1 | Pyrazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2007-08-23 | — | — | US | disclosed |
| US-20060276478-A1 | Pyrazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2006-12-07 | — | — | US | disclosed |
| EP-1694681-A1 | PYRAZOLOPYRIMIDINES | Bayer CropScience AG (DE) | 2006-08-30 | — | — | EP | disclosed |
| US-20060089499-A1 | Pyrazolopyrimidines and the use thereof for controlling harmful organisms | UWW VENTURES UNLIMITED (GB) | 2006-04-27 | — | — | US | disclosed |
| WO-2005056556-A1 | PYRAZOLOPYRIMIDINES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060089499-A1 | Pyrazolopyrimidines and the use thereof for controlling harmful organisms | PRDX1, PRDX2, PRDX5 | CDK2 154/4885PDE2A 1181/4885CSNK2A1 2382/4885 |
| US-20070197540-A1 | Pyrazolopyrimidines | QDPR, Q6ZSR9, RPLP2 | CDK2 117/4885PDE2A 1118/4885CSNK2A1 2716/4885 |
| US-20070259893-A1 | microbicides, fungicides; 7-amino-pyrazolo(1,5-a)pyrimidines; controlling unwanted microorganisms | PNPO, CYP4X1, CYP1B1 | CDK2 1161/4885PDE2A 493/4885CSNK2A1 4793/4885 |
| US-20060276478-A1 | Pyrazolopyrimidines | Q6ZSR9, RPLP2, DPYD | CDK2 200/4885PDE2A 1630/4885CSNK2A1 3066/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.