Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5320636 | 0.88 | CSNK2A1 (0.48) | CSNK2A1ALDH1A1KDM4EHPGDGLA | |
| SCHEMBL5326152 | 0.88 | KDM4E (0.54) | CSNK2A1ALDH1A1KDM4EHPGDGLA | |
| SCHEMBL5323448 | 0.87 | CSNK2A1 (0.47) | CSNK2A1ALDH1A1KDM4EHPGDGLA | |
| SCHEMBL5321374 | 0.84 | KDM4E (0.47) | CSNK2A1ALDH1A1KDM4EHPGDGLA | |
| SCHEMBL5594559 | 0.82 | CSNK2A1 (0.43) | CSNK2A1ALDH1A1KDM4EHPGDGLA | |
| SCHEMBL14463752 | 0.75 | CDK2 (0.54) | CSNK2A1ALDH1A1KDM4EHPGDGLA | |
| SCHEMBL5325823 | 0.74 | CDK2 (0.40) | CSNK2A1ALDH1A1KDM4EHPGDGLA | |
| SCHEMBL973763 | 0.73 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDGLAMAPK1 | |
| SCHEMBL14463868 | 0.72 | CDK2 (0.47) | CSNK2A1ALDH1A1KDM4EHPGDGLA | |
| SCHEMBL14423710 | 0.70 | AR (0.40) | CSNK2A1KDM4ECDK2HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007118844-A1 | SUBSTITUTED PYRAZOLOPYRIMIDINES, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR CONTROLLING HARMFUL FUNGI AND COMPOSITIONS COMPRISING THEM | BASF SE (DE) | 2007-10-25 | — | — | WO | disclosed |