SCHEMBL14464243

SCHEMBL14464243

C=CC(=C)OCCOc1ccc(C(C)(C)c2ccc(OCCOCCOC(=O)C=C)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.53
ALDH1A1 P00352 9/20 0.46
TSHR P16473 3/20 0.46
TP53 P04637 2/20 0.46
HIF1A Q16665 2/20 0.46
HSD17B10 Q99714 1/20 0.46
KDM4E B2RXH2 9/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
GAA P10253 1/20 0.43
POLB P06746 2/20 0.41
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
HTT P42858 1/20 0.40
LMNA P02545 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
HPGD P15428 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14464239 0.96 THRB (0.57) THRBALDH1A1TSHRTP53HIF1A
SCHEMBL6292051 0.94 THRB (0.60) THRBALDH1A1TSHRTP53HIF1A
SCHEMBL16919771 0.94 THRB (0.60) THRBALDH1A1TSHRTP53HIF1A
SCHEMBL19770675 0.94 THRB (0.60) THRBALDH1A1TSHRTP53HIF1A
SCHEMBL16804047 0.94 THRB (0.60) THRBALDH1A1TSHRTP53HIF1A
SCHEMBL12281676 0.94 THRB (0.60) THRBALDH1A1TSHRTP53HIF1A
SCHEMBL7631129 0.94 THRB (0.60) THRBALDH1A1TSHRTP53HIF1A
SCHEMBL8907758 0.92 ALDH1A1 (0.43) THRBALDH1A1TSHRTP53HIF1A
SCHEMBL14173110 0.90 THRB (0.65) THRBALDH1A1TSHRTP53HIF1A
SCHEMBL137572 0.90 THRB (0.65) THRBALDH1A1TSHRTP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8809413-B2 Ultraviolet radiation-curable high refractive index optically clear resins HA CHAU (US) 2014-08-19 US disclosed
US-20130004676-A1 ULTRAVIOLET RADIATION-CURABLE HIGH REFRACTIVE INDEX OPTICALLY CLEAR RESINS HA CHAU (US) 2013-01-03 US disclosed