Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6171023 | 0.86 | ALDH1A1 (0.47) | ALDH1A1GAAMAPTHPGDKDM4E | |
| SCHEMBL6171017 | 0.86 | ALDH1A1 (0.47) | ALDH1A1GAAMAPTHPGDKDM4E | |
| SCHEMBL20203376 | 0.83 | ALDH1A1 (0.55) | ALDH1A1GAAGFERMAPTHPGD | |
| SCHEMBL3167924 | 0.80 | MAPT (0.49) | ALDH1A1GAAMAPTHPGDKDM4E | |
| SCHEMBL3167942 | 0.80 | MAPT (0.49) | ALDH1A1GAAMAPTHPGDKDM4E | |
| SCHEMBL9205940 | 0.79 | LTB4R (0.52) | ALDH1A1GAAGFERMAPTHPGD | |
| SCHEMBL6169914 | 0.78 | ALDH1A1 (0.50) | ALDH1A1GAAMAPTHPGDKDM4E | |
| SCHEMBL6169905 | 0.78 | ALDH1A1 (0.50) | ALDH1A1GAAMAPTHPGDKDM4E | |
| SCHEMBL6169288 | 0.78 | ALDH1A1 (0.50) | ALDH1A1GAAMAPTHPGDKDM4E | |
| SCHEMBL6169292 | 0.78 | ALDH1A1 (0.50) | ALDH1A1GAAMAPTHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007081335-A1 | THERAPEUTIC COMPOUNDS FOR TREATING DYSLIPIDEMIC CONDITIONS | MERCK & CO., INC. (US) | 2007-07-19 | — | — | WO | disclosed |