Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 10/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14465342 | 0.83 | ALDH1A1 (0.55) | ALDH1A1GAAGFERCYP4F2CYP4A11 | |
| SCHEMBL17356365 | 0.77 | EGFR (0.38) | ALDH1A1GAAMAPTKDM4E | |
| SCHEMBL30565426 | 0.77 | ALDH1A1 (0.75) | ALDH1A1GAAGFERCYP4F2CYP4A11 | |
| SCHEMBL7237331 | 0.77 | ALDH1A1 (0.75) | ALDH1A1GAAGFERCYP4F2CYP4A11 | |
| SCHEMBL15184525 | 0.76 | ALDH1A1 (0.64) | ALDH1A1GAAGFERCYP4F2CYP4A11 | |
| SCHEMBL14641355 | 0.76 | CYP4F2 (0.55) | ALDH1A1GAAGFERCYP4F2CYP4A11 | |
| SCHEMBL18232223 | 0.74 | ALDH1A1 (0.53) | ALDH1A1GAAGFERCYP4F2CYP4A11 | |
| SCHEMBL8151837 | 0.74 | ALDH1A1 (0.66) | ALDH1A1GAAGFERCYP4F2CYP4A11 | |
| SCHEMBL3213276 | 0.74 | ALDH1A1 (0.66) | ALDH1A1GAAGFERCYP4F2CYP4A11 | |
| SCHEMBL30026686 | 0.74 | ALDH1A1 (0.66) | ALDH1A1GAAGFERCYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018096159-A1 | OXADIAZOLONES AS TRANSIENT RECEPTOR POTENTIAL CHANNEL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2018-05-31 | — | — | WO | disclosed |