SCHEMBL14465445

SCHEMBL14465445

CCn1c2ccccc2c2cc(N(C)c3ccc(-c4ccccc4)cc3)ccc21

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.52
KDM4E B2RXH2 4/20 0.52
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
HTT P42858 2/20 0.52
MAPK1 P28482 2/20 0.52
ALDH1A1 P00352 1/20 0.52
HPGD P15428 1/20 0.52
HBB P68871 1/20 0.52
HSD17B10 Q99714 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
NPY5R Q15761 4/20 0.50
TSPO P30536 1/20 0.50
RAC2 P15153 1/20 0.48
RAC3 P60763 1/20 0.48
CDC42 P60953 1/20 0.48
RAC1 P63000 1/20 0.48
DRD3 P35462 1/20 0.47
LMNA P02545 3/20 0.47
RORC P51449 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL279090 0.93 MAPT (0.56) MAPTKDM4EMEN1KMT2AHTT
SCHEMBL14465461 0.92 MAPT (0.50) MAPTKDM4EMEN1KMT2AHTT
SCHEMBL14119381 0.89 KDM4E (0.55) MAPTKDM4EMEN1KMT2AHTT
SCHEMBL14465443 0.87 MAPT (0.55) MAPTKDM4EMEN1KMT2AHTT
SCHEMBL2368754 0.86 KDM4E (0.55) MAPTKDM4EMEN1KMT2AHTT
SCHEMBL14465444 0.85 MAPT (0.51) MAPTKDM4EMEN1KMT2AHTT
SCHEMBL13803413 0.84 TSPO (0.57) MAPTKDM4EMEN1KMT2AHTT
SCHEMBL13803326 0.84 TSPO (0.57) MAPTKDM4EMEN1KMT2AHTT
SCHEMBL13803329 0.84 TSPO (0.57) MAPTKDM4EMEN1KMT2AHTT
SCHEMBL13803423 0.84 TSPO (0.57) MAPTKDM4EMEN1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9048436-B2 Oxadiazole derivative, and light emitting element, light emitting device, and electronic device using the oxadiazole derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-06-02 US disclosed
EP-1976838-B1 OXADIAZOLE DERIVATIVE, AND LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE, AND ELECTRONIC DEVICE USING THE OXADIAZOLE DERIVATIVE SEMICONDUCTOR ENERGY LAB (JP) 2015-02-25 EP disclosed
US-20140299822-A1 Oxadiazole Derivative, and Light Emitting Element, Light Emitting Device, and Electronic Device Using the Oxadiazole Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-10-09 US disclosed
US-20130200344-A1 Oxadiazole Derivative, and Light Emitting Element, Light Emitting Device, and Electronic Device Using the Oxadiazole Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-08-08 US disclosed
US-8389735-B2 Oxadiazole derivative, and light emitting element, light emitting device, and electronic device using the oxadiazole derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-03-05 US disclosed
WO-2007074893-A1 OXADIAZOLE DERIVATIVE, AND LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE, AND ELECTRONIC DEVICE USING THE OXADIAZOLE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-07-05 WO disclosed
US-20070149784-A1 Oxadiazole derivative, and light emitting element, light emitting device, and electronic device using the oxadiazole derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2007-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070149784-A1 Oxadiazole derivative, and light emitting element, light emitting device, and electronic device using the oxadiazole derivative OXA1L, ADRA1D, CRY1 MAPT 3287/4885KDM4E 4218/4885MEN1 475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.