SCHEMBL144666

SCHEMBL144666

Nc1ccc(C(=O)c2ccccc2)cc1[N+](=O)[O-]

nearest known ligand 0.77

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.77
LMNA P02545 2/20 0.71
VCAM1 P19320 2/20 0.68
MEN1 O00255 3/20 0.63
KMT2A Q03164 3/20 0.63
MAPT P10636 2/20 0.63
CRHBP P24387 1/20 0.59
CRHR2 Q13324 1/20 0.59
POLB P06746 2/20 0.53
TDP1 Q9NUW8 3/20 0.51
ALDH1A1 P00352 2/20 0.51
CYP3A4 P08684 1/20 0.51
ALOX15 P16050 1/20 0.51
CES2 O00748 1/20 0.51
CES1 P23141 1/20 0.51
KDM4E B2RXH2 1/20 0.51
PBRM1 Q86U86 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6806851 1.00 MAPK1 (0.77) MAPK1LMNAVCAM1MEN1KMT2A
SCHEMBL865520 0.92 LMNA (0.77) MAPK1LMNAVCAM1MEN1KMT2A
SCHEMBL31174170 0.92 LMNA (0.77) MAPK1LMNAVCAM1MEN1KMT2A
SCHEMBL9352340 0.87 LMNA (0.71) MAPK1LMNAVCAM1MEN1KMT2A
SCHEMBL11714590 0.87 LMNA (0.66) MAPK1LMNAVCAM1MEN1KMT2A
SCHEMBL11014246 0.87 MAPK1 (1.00) MAPK1LMNAVCAM1MEN1KMT2A
SCHEMBL10477444 0.86 LMNA (0.64) MAPK1LMNAVCAM1MEN1KMT2A
SCHEMBL11025417 0.86 TSHR (0.65) MAPK1LMNAVCAM1MEN1KMT2A
SCHEMBL1625752 0.86 LMNA (0.64) MAPK1LMNAVCAM1MEN1KMT2A
SCHEMBL10808103 0.86 LMNA (0.64) MAPK1LMNAVCAM1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116874383-A Benzophenone LED visible light initiator and preparation method and application thereof 贵州师范学院 2023-10-13 CN claimed
CN-109467512-B Synthetic method of 3, 4-diamino-benzophenone 苏州开元民生科技股份有限公司 2021-06-08 CN claimed
EP-2613819-B2 LUBRICIOUS COATINGS FOR MEDICAL DEVICES BIOINTERACTIONS LTD (GB) 2020-11-25 EP claimed
CN-109467512-A A kind of synthetic method of 3,4- diamino-benzophenone 苏州开元民生科技股份有限公司 2019-03-15 CN claimed
CN-106083622-B A kind of preparation method of mebendazole intermediate 3,4- diaminobenzophenones 常州齐晖药业有限公司 2018-06-19 CN claimed
CN-108059602-A A kind of preparation method of oxyclozanide intermediate 2-amino -4,6- chlorophenesic acid organic solution 常州齐晖药业有限公司 2018-05-22 CN claimed
EP-2613819-B1 LUBRICIOUS COATINGS FOR MEDICAL DEVICES BIOINTERACTIONS LTD (GB) 2018-01-10 EP claimed
CN-106083622-A A kind of preparation method of mebendazole intermediate 3,4 diaminobenzophenone 常州齐晖药业有限公司 2016-11-09 CN claimed
CN-103209717-B Lubricious coatings for medical devices BIOINTERACTIONS LTD 2015-04-08 CN claimed
US-8541498-B2 Lubricious coatings for medical devices BIOINTERACTIONS LTD. (GB) 2013-09-24 US claimed
EP-2613819-A1 Lubricious coatings for medical devices Biointeractions Ltd. (GB) 2013-07-17 EP claimed
WO-2012032283-A1 Lubricious coatings for medical devices BIOINTERACTIONS LTD (GB) 2012-03-15 WO claimed
US-20120059111-A1 LUBRICIOUS COATINGS FOR MEDICAL DEVICES BIOINTERACTIONS LTD. (GB) 2012-03-08 US claimed
CN-101668425-A Tri-aryl/heteroaroaromatic cannabinoids and use thereof UNIV TENNESSEE RES FOUNDATION 2010-03-10 CN claimed
US-7087641-B2 4β-1″-[(2″-substituted benzoyl) anilino]podophyllotoxin analogues useful as anticancer agents COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2006-08-08 US claimed
EP-1377588-B1 4-BETA-1''-[(2''-(SUBSTITUTED BENZOYL)ANILINO] PODOPHYLLOTOXIN ANALOGUES USEFUL AS ANTICANCER AGENTS COUNCIL SCIENT IND RES (IN) 2005-08-10 EP claimed
US-20050101804-A1 4Beta-1\"-{2'-substituted benzoyl) anilino] podophyllotoxin analogues useful as anticancer agents COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2005-05-12 US claimed
EP-1377588-A1 4-BETA-1''-[(2''-(SUBSTITUTED BENZOYL)ANILINO] PODOPHYLLOTOXIN ANALOGUES USEFUL AS ANTICANCER AGENTS COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2004-01-07 EP claimed
WO-2003082876-A1 4-BETA-1''-`(2''-(SUBSTITUTED BENZOYL)ANILINO! PODOPHYLLOTOXIN ANALOGUES USEFUL AS ANTICANCER AGENTS COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2003-10-09 WO claimed
US-4909608-A Optical monlinearity of aminobenzophenone derivatives MARTIN MARIETTA CORPORATION (US) 1990-03-20 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050101804-A1 4Beta-1\"-{2'-substituted benzoyl) anilino] podophyllotoxin analogues useful as anticancer agents TUBB4A, CASP4, TUBB4B MAPK1 3075/4885LMNA 190/4885VCAM1 1929/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.