Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 6/20 | 0.74 |
| ▸ | SIRT7 | Q9NRC8 | 1/20 | 0.71 |
| ▸ | FLT1 | P17948 | 3/20 | 0.56 |
| ▸ | KDR | P35968 | 3/20 | 0.56 |
| ▸ | FLT4 | P35916 | 2/20 | 0.56 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.47 |
| ▸ | SRC | P12931 | 2/20 | 0.47 |
| ▸ | FLT3 | P36888 | 2/20 | 0.47 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.47 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.47 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.47 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.47 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.47 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.47 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14465944 | 0.85 | VCP (1.00) | VCPSIRT7FLT1KDRFLT4 | |
| SCHEMBL5319550 | 0.84 | VCP (0.72) | VCPSIRT7FLT1KDRFLT4 | |
| SCHEMBL23540651 | 0.82 | VCP (0.69) | VCPSIRT7FLT1KDRFLT4 | |
| SCHEMBL5319705 | 0.82 | VCP (0.69) | VCPSIRT7FLT1KDRFLT4 | |
| SCHEMBL5317574 | 0.81 | VCP (0.68) | VCPSIRT7FLT1KDRFLT4 | |
| SCHEMBL5322309 | 0.78 | VCP (0.67) | VCPSIRT7FLT1KDRFLT4 | |
| SCHEMBL5324022 | 0.78 | VCP (0.62) | VCPSIRT7FLT1KDRFLT4 | |
| SCHEMBL14466048 | 0.78 | SIRT7 (0.61) | VCPSIRT7FLT1KDRFLT4 | |
| SCHEMBL5319106 | 0.77 | SIRT7 (0.64) | VCPSIRT7FLT1KDRFLT4 | |
| SCHEMBL22925926 | 0.77 | VCP (0.62) | VCPSIRT7FLT1KDRFLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007076161-A2 | COMPOUNDS WITH THERAPEUTIC ACTIVITY | MYRIAD GENETICS, INC (US) | 2007-07-05 | — | — | WO | disclosed |