Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT7 | Q9NRC8 | 1/20 | 0.64 |
| ▸ | VCP | P55072 | 3/20 | 0.63 |
| ▸ | KDR | P35968 | 6/20 | 0.57 |
| ▸ | FLT1 | P17948 | 4/20 | 0.57 |
| ▸ | FLT4 | P35916 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5319550 | 0.84 | VCP (0.72) | SIRT7VCPKDRFLT1FLT4 | |
| SCHEMBL14465944 | 0.77 | VCP (1.00) | SIRT7VCPKDRFLT1FLT4 | |
| SCHEMBL14466945 | 0.77 | VCP (0.74) | SIRT7VCPKDRFLT1FLT4 | |
| SCHEMBL5316742 | 0.77 | SIRT7 (0.60) | SIRT7VCPKDRFLT1FLT4 | |
| SCHEMBL5319683 | 0.76 | KDR (0.78) | SIRT7VCPKDRFLT1FLT4 | |
| SCHEMBL22925926 | 0.75 | VCP (0.62) | SIRT7VCPKDRFLT1FLT4 | |
| SCHEMBL29620924 | 0.75 | VCP (0.62) | SIRT7VCPKDRFLT1FLT4 | |
| SCHEMBL5316979 | 0.75 | TRPV1 (0.74) | SIRT7VCPKDRFLT1FLT4 | |
| SCHEMBL28733707 | 0.75 | TRPV1 (0.55) | SIRT7VCPKDRFLT1FLT4 | |
| SCHEMBL23540651 | 0.74 | VCP (0.69) | SIRT7VCPKDRFLT1FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007076161-A2 | COMPOUNDS WITH THERAPEUTIC ACTIVITY | MYRIAD GENETICS, INC (US) | 2007-07-05 | — | — | WO | claimed |
| WO-2007076161-A2 | COMPOUNDS WITH THERAPEUTIC ACTIVITY | MYRIAD GENETICS, INC (US) | 2007-07-05 | — | — | WO | disclosed |
| WO-2007076161-A2 | COMPOUNDS WITH THERAPEUTIC ACTIVITY | MYRIAD GENETICS, INC (US) | 2007-07-05 | — | — | WO | disclosed |