Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 7/20 | 0.67 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.54 |
| ▸ | SIRT7 | Q9NRC8 | 1/20 | 0.52 |
| ▸ | FLT1 | P17948 | 6/20 | 0.48 |
| ▸ | KDR | P35968 | 6/20 | 0.48 |
| ▸ | FLT4 | P35916 | 5/20 | 0.48 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.44 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.44 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.44 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.44 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.44 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5317562 | 0.89 | VCP (0.61) | VCPPIK3CGSIRT7FLT1KDR | |
| SCHEMBL5319681 | 0.88 | VCP (0.65) | VCPFLT1KDRFLT4 | |
| SCHEMBL5319705 | 0.82 | VCP (0.69) | VCPPIK3CGSIRT7FLT1KDR | |
| SCHEMBL14466947 | 0.82 | VCP (0.65) | VCPPIK3CGSIRT7FLT1KDR | |
| SCHEMBL28733638 | 0.81 | VCP (0.60) | VCPPIK3CGSIRT7FLT1KDR | |
| SCHEMBL14465944 | 0.80 | VCP (1.00) | VCPPIK3CGSIRT7FLT1KDR | |
| SCHEMBL14466945 | 0.78 | VCP (0.74) | VCPPIK3CGSIRT7FLT1KDR | |
| SCHEMBL21303773 | 0.77 | VCP (0.62) | VCPPIK3CGSIRT7FLT1KDR | |
| SCHEMBL28733778 | 0.77 | VCP (0.64) | VCPPIK3CGSIRT7FLT1KDR | |
| SCHEMBL5319878 | 0.77 | FLT1 (0.76) | VCPSIRT7FLT1KDRFLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007076161-A2 | COMPOUNDS WITH THERAPEUTIC ACTIVITY | MYRIAD GENETICS, INC (US) | 2007-07-05 | — | — | WO | claimed |
| WO-2007076161-A2 | COMPOUNDS WITH THERAPEUTIC ACTIVITY | MYRIAD GENETICS, INC (US) | 2007-07-05 | — | — | WO | disclosed |