Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27777630 | 0.92 | KMT2A (0.56) | KMT2ASLC6A2SLC6A3TDP1TSHR | |
| SCHEMBL17797868 | 0.84 | TSHR (0.47) | KMT2ATSHRTP53LMNAPDCD1 | |
| SCHEMBL823029 | 0.84 | TSHR (0.57) | KMT2ATDP1TSHRTP53LMNA | |
| SCHEMBL28522669 | 0.83 | TSHR (0.46) | KMT2ATSHRTP53LMNAPDCD1 | |
| SCHEMBL3701482 | 0.82 | TSHR (0.48) | KMT2ASLC6A2SLC6A3TDP1TSHR | |
| SCHEMBL17797881 | 0.79 | LMNA (0.47) | KMT2ATDP1TSHRTP53LMNA | |
| SCHEMBL6384996 | 0.79 | ALDH1A1 (0.42) | KMT2ATSHRLMNACYP2D6ALDH1A1 | |
| SCHEMBL16805842 | 0.79 | PDCD1 (0.58) | KMT2ASLC6A3TSHRTP53LMNA | |
| SCHEMBL28622308 | 0.78 | LMNA (0.46) | KMT2ATDP1TSHRTP53LMNA | |
| SCHEMBL16278308 | 0.78 | LMNA (0.46) | KMT2ATDP1TSHRTP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8754019-B2 | Pressure transmission medium and hydraulic device | IDEMITSU KOSAN CO., LTD. (JP) | 2014-06-17 | — | — | US | disclosed |
| US-20110105373-A1 | PRESSURE TRANSMISSION MEDIUM AND HYDRAULIC DEVICE | IDEMITSU KOSAN CO., LTD. (JP) | 2011-05-05 | — | — | US | disclosed |
| EP-2302022-A1 | PRESSURE TRANSMISSION MEDIUM AND HYDRAULIC DEVICE | Idemitsu Kosan Co., Ltd. (JP) | 2011-03-30 | — | — | EP | disclosed |